# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4305041 | B | Selectivity ratio of IC50 for human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells to IC50 for human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 insect cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA4305042 | B | Inhibition of human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay | Homo sapiens | 62 | cell-based format | Scientific Literature | ||
3. | ALA4305044 | B | Inhibition of human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 insect cells using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay | Homo sapiens | 62 | cell-based format | Scientific Literature | ||
4. | ALA4305046 | B | Inhibition of human full-length N-terminal GST-tagged PARP3 expressed in baculovirus infected Sf9 insect cells at 500 nM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA4305047 | B | Inhibition of human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected Sf9 insect cells at 500 nM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA4305048 | B | Inhibition of human N-terminal GST-tagged TNKS2 (667 to 1166 residues) expressed in baculovirus infected Sf9 insect cells at 500 nM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA4305049 | B | Inhibition of PARP8 (unknown origin) at 500 nM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
8. | ALA4305050 | B | Inhibition of human N-terminal FLAG-tagged/C-terminal Strep-tagged PARP10 (805 to 1025 residues) expressed in baculovirus infected Sf9 insect cells at 500 nM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
9. | ALA4305051 | B | Inhibition of human N-terminal His/GST-tagged PARP14 (1470 to 1801 residues) expressed in baculovirus infected Sf9 insect cells at 500 nM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
10. | ALA4305074 | F | Cytotoxicity against BRCA1-proficient human SUM149 cells measured after 6 days by microscopic analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
11. | ALA4305075 | F | Selectivity ratio of EC50 for BRCA1-proficient human SUM149 cells to EC50 for BRCA1-deficient human SUM149 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA4305076 | F | Cytotoxicity against BRCA1-deficient human SUM149 cells measured after 6 days by microscopic analysis | Homo sapiens | 4 | cell-based format | Scientific Literature |