| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4416694 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/34(H1N1)) infected in human A549 cells assessed as reduction in virus neuraminidase level incubated for 24 hrs by fluorescence based assay | Influenza A virus | 5 | ALA4414632 | organism-based format | Scientific Literature | |
| 2. | ALA4416695 | T | Therapeutic index, ratio of CC50 for human A549 cells to IC50 for Influenza A virus (A/Puerto Rico/8/34(H1N1)) | 5 | ALA4414632 | assay format | Scientific Literature | ||
| 3. | ALA4416696 | T | Therapeutic index, ratio of CC50 for dog MDCK cells to IC50 for Influenza A virus (A/Taiwan/1/1986(H1N1)) | 5 | ALA4414632 | assay format | Scientific Literature | ||
| 4. | ALA4416697 | T | Therapeutic index, ratio of CC50 for dog MDCK cells to IC50 for Influenza A virus A/Virginia/3/1975 (H3N2) | 5 | ALA4414632 | assay format | Scientific Literature | ||
| 5. | ALA4416698 | F | Antiviral activity against Influenza A virus A/Virginia/3/1975 (H3N2) infected in MDCK cells assessed as reduction in virus-induced cytopathic effect by measuring ATP level incubated for 24 hrs by ATPlite luminescence assay | Influenza A virus | 5 | ALA4414632 | organism-based format | Scientific Literature | |
| 6. | ALA4416699 | F | Antiviral activity against Influenza A virus (A/Taiwan/1/1986(H1N1)) infected in MDCK cells assessed as reduction in virus-induced cytopathic effect by measuring ATP level incubated for 24 hrs by ATPlite luminescence assay | Influenza A virus | 5 | ALA4414632 | organism-based format | Scientific Literature | |
| 7. | ALA4416700 | B | Displacement of gamma-[6-aminohexyl]-GTP-biotin from Influenza A virus A/Victoria/3/1975 (H3N2) N-terminal 6His-tagged PB2 (320 to 484 residues) expressed in Escherichia coli incubated for 1 hr by TR-FRET assay | Influenza A virus (A/Victoria/3/1975(H3N2)) | 4 | ALA4414632 | assay format | Scientific Literature | |
| 8. | ALA4416701 | B | Displacement of gamma-[6-aminohexyl]-GTP-biotin from Influenza B virus B/Brisbane/60/2008 C-terminal 6His-tagged PB2 (320 to 484 residues) expressed in Escherichia coli incubated for 1 hr by TR-FRET assay | Influenza B virus (B/Brisbane/60/2008) | 4 | ALA4414632 | assay format | Scientific Literature | |
| 9. | ALA4416702 | A | Stability in human liver microsomes assessed as intrinsic clearance | Homo sapiens | 1 | ALA4414632 | microsome format | Scientific Literature | |
| 10. | ALA4416703 | T | Genotoxicity in human TK6 cells assessed as reduction in formation of micronuclei | Homo sapiens | 1 | ALA4414632 | cell-based format | Scientific Literature | |
| 11. | ALA4416704 | B | Inhibition of human ERG transfected in human HEK293 cell membrane by liquid scintillation counting method | Homo sapiens | 1 | ALA4414632 | cell-based format | Scientific Literature | |
| 12. | ALA4416705 | A | Substrate activity at aldehyde oxidase in human liver cytosol assessed as compound remaining at 1 uM incubated for 60 mins by LC-MS analysis | Homo sapiens | 1 | ALA4414632 | subcellular format | Scientific Literature | |
| 13. | ALA4416706 | A | Protein binding in human plasma at 1 uM incubated for 6 hrs in orbital shaker by LC-MS/MS analysis | Homo sapiens | 1 | ALA4414632 | cell-free format | Scientific Literature | |
| 14. | ALA4416707 | A | Protein binding in mouse plasma at 1 uM incubated for 6 hrs in orbital shaker by LC-MS/MS analysis | Mus musculus | 1 | ALA4414632 | cell-free format | Scientific Literature | |
| 15. | ALA4416708 | A | Protein binding in dog plasma at 1 uM incubated for 6 hrs in orbital shaker by LC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4414632 | cell-free format | Scientific Literature | |
| 16. | ALA4416709 | A | Stability in mouse liver microsomes assessed as intrinsic clearance | Mus musculus | 1 | ALA4414632 | microsome format | Scientific Literature | |
| 17. | ALA4416710 | A | Stability in dog liver microsomes assessed as intrinsic clearance | Canis lupus familiaris | 1 | ALA4414632 | microsome format | Scientific Literature | |
| 18. | ALA4416711 | A | Cmax in BALB/c mouse at 10 mg/kg, po | Mus musculus | 1 | ALA4414632 | organism-based format | Scientific Literature | |
| 19. | ALA4416712 | A | Tmax in BALB/c mouse at 10 mg/kg, po | Mus musculus | 1 | ALA4414632 | organism-based format | Scientific Literature | |
| 20. | ALA4416713 | A | AUClast in BALB/c mouse at 10 mg/kg, po | Mus musculus | 1 | ALA4414632 | organism-based format | Scientific Literature |
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