| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4360722 | Binding | Displacement of [3H]JWH-018 from CB1R/CB2R in Wistar rat brain membranes after 60 mins by liquid scintillation analysis | Rattus norvegicus | 26 | ALA4359826 | cell membrane format | Scientific Literature | |
| 2. | ALA4360725 | Binding | Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes after 60 mins by liquid scintillation analysis | Rattus norvegicus | 17 | ALA4359826 | cell membrane format | Scientific Literature | |
| 3. | ALA4360726 | Binding | Displacement of [3H]Ile5,6-deltorphin-2 from DOR in Wistar rat brain membranes after 60 mins by liquid scintillation analysis | Rattus norvegicus | 17 | ALA4359826 | cell membrane format | Scientific Literature | |
| 4. | ALA4360727 | Binding | Displacement of [3H]HS-665 from KOR in guinea pig brain membranes after 60 mins by liquid scintillation analysis | Cavia porcellus | 17 | ALA4359826 | cell membrane format | Scientific Literature | |
| 5. | ALA4360728 | Binding | Selectivity ratio, ratio of Ki for displacement of [3H]Ile5,6-deltorphin-2 from DOR in Wistar rat brain membranes to Ki for displacement of [3H]DAMGO from MOR in Wistar rat brain membranes | Rattus norvegicus | 13 | ALA4359826 | cell membrane format | Scientific Literature | |
| 6. | ALA4360729 | Binding | Selectivity ratio of Ki for displacement of [3H]HS-665 from KOR in guinea pig brain membranes to Ki for displacement of [3H]DAMGO from MOR in Wistar rat brain membranes | 12 | ALA4359826 | cell membrane format | Scientific Literature | ||
| 7. | ALA4360730 | Binding | Displacement of [3H]WIN-55,212-2 from CB1R/CB2R in Wistar rat brain membranes after 60 mins by liquid scintillation analysis | Rattus norvegicus | 17 | ALA4359826 | cell membrane format | Scientific Literature | |
| 8. | ALA4360731 | Binding | Agonist activity at MOR/CB1R/CB2R receptor in Wistar rat brain membranes after 60 mins by [35S]-GTPgammaS binding assay | Rattus norvegicus | 14 | ALA4359826 | cell membrane format | Scientific Literature | |
| 9. | ALA4360732 | Functional | Agonist activity at MOR in Wistar rat brain membranes at 10 uM in presence of naloxone after 60 mins by [35S]-GTPgammaS binding assay relative to control | Rattus norvegicus | 2 | ALA4359826 | cell membrane format | Scientific Literature | |
| 10. | ALA4360733 | Functional | Agonist activity at CB1R in Wistar rat brain membranes at 10 uM in presence of rimonabant after 60 mins by [35S]-GTPgammaS binding assay relative to control | Rattus norvegicus | 2 | ALA4359826 | cell membrane format | Scientific Literature | |
| 11. | ALA4360734 | Functional | Agonist activity at CB2R in Wistar rat brain membranes at 10 uM in presence of AM630 after 60 mins by [35S]-GTPgammaS binding assay relative to control | Rattus norvegicus | 2 | ALA4359826 | cell membrane format | Scientific Literature | |
| 12. | ALA4360735 | Binding | Agonist activity at MOR/CB1R/CB2R in Wistar rat brain membranes at 10 uM in presence of naloxone,rimonabant and AM630 after 60 mins by [35S]-GTPgammaS binding assay relative to control | Rattus norvegicus | 2 | ALA4359826 | cell membrane format | Scientific Literature | |
| 13. | ALA4360736 | Functional | Agonist activity at MOR in Wistar rat brain membranes in presence of naloxone after 60 mins by [35S]-GTPgammaS binding assay | Rattus norvegicus | 2 | ALA4359826 | cell membrane format | Scientific Literature | |
| 14. | ALA4360737 | Functional | Agonist activity at CB1R in Wistar rat brain membranes in presence of rimonabant after 60 mins by [35S]-GTPgammaS binding assay | Rattus norvegicus | 2 | ALA4359826 | cell membrane format | Scientific Literature | |
| 15. | ALA4360738 | Functional | Agonist activity at CB2R in Wistar rat brain membranes in presence of AM630 after 60 mins by [35S]-GTPgammaS binding assay | Rattus norvegicus | 2 | ALA4359826 | cell membrane format | Scientific Literature | |
| 16. | ALA4360740 | ADME | Permeability across apical to basolateral side in rat brain Astroglial/Endothelial cells at 0.25 to 0.75 uM after 15 to 60 mins by liquid scintillation analysis | Rattus norvegicus | 2 | ALA4359826 | assay format | Scientific Literature | |
| 17. | ALA4360741 | Functional | Antinociceptive activity in CD-1 mouse assessed as increase in thermal latency at 10 mg/kg, iv after 15 to 120 mins by hot plate technique | Mus musculus | 2 | ALA4359826 | organism-based format | Scientific Literature | |
| 18. | ALA4360742 | ADME | Effect on nociception of the contralateral paw in rat model of sodium iodoacetate-induced osteoarthritis paw withdrawal threshold in early phase at 20 ug administered as intrathecal injection measured up to 45 mins by Von Frey test (Rvb = 44 +/- 2.4 g) | Rattus norvegicus | 4 | ALA4359826 | organism-based format | Scientific Literature | |
| 19. | ALA4360743 | ADME | Effect on nociception of the contralateral paw in rat model of sodium iodoacetate-induced osteoarthritis paw withdrawal threshold in late phase at 20 ug administered as intrathecal injection measured after 60 to 90 mins by Von Frey test (Rvb = 43 +/- 3.4 g) | Rattus norvegicus | 4 | ALA4359826 | organism-based format | Scientific Literature | |
| 20. | ALA4360746 | Functional | Antiallodynic activity in sodium iodoacetate-induced rat model of osteoarthritis assessed as increase in maximum effect in early phase at 20 ug administered as intrathecal injection measured up to 45 mins by Von Frey test | Rattus norvegicus | 4 | ALA4359826 | organism-based format | Scientific Literature |
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