#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4409553	Binding	Inhibition of IFN-gamma-induced human TDO2 transfected in HeLa cells at 10 times IDO1 IC50 concentration using L-tryptophan as substrate incubated for 24 hrs relative to control	Homo sapiens	6	ALA4406863	cell-based format	Scientific Literature
2.	ALA4409554	Binding	Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 24 hrs	Homo sapiens	37	ALA4406863	cell-based format	Scientific Literature
3.	ALA4409555	ADME	Cytotoxicity against human HeLa cells assessed as survival rate at 30 uM incubated for 24 hrs by MTT assay relative to control	Homo sapiens	36	ALA4406863	cell-based format	Scientific Literature
4.	ALA4409556	Binding	Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production at 30 uM using L-tryptophan as substrate incubated for 24 hrs relative to control	Homo sapiens	36	ALA4406863	cell-based format	Scientific Literature
5.	ALA4409558	Binding	Reversal of IDO1-mediated immunosuppression in mouse CT26 co-cultured with T-cells assessed as increase in T cell proliferation measured after 48 hrs by MTT assay	Mus musculus	3	ALA4406863	assay format	Scientific Literature
6.	ALA4409559	Binding	Reversal of IDO1-mediated immunosuppression in mouse CT26 co-cultured with T-cells assessed as increase in IFN-gamma production measured after 48 hrs by ELISA	Mus musculus	1	ALA4406863	assay format	Scientific Literature
7.	ALA4409560	Binding	Reversal of IDO1-mediated immunosuppression in mouse CT26 co-cultured with T-cells assessed as ConA- stimulated differentiation of Treg cells at 0.3 uM measured after 48 hrs by FOXP3-APC based flow cytometry analysis (Rvb = 11.4 %)	Mus musculus	3	ALA4406863	assay format	Scientific Literature
8.	ALA4409561	Functional	Antitumor activity against mouse CT26 cells xenografted in BALB/c mouse assessed as decrease in tumour growth at 50 mg/kg, po via gavage for 17 days by vernier caliper method	Mus musculus	2	ALA4406863	organism-based format	Scientific Literature
9.	ALA4409566	Functional	Induction of apoptosis in BALB/c mouse xenografted with CT26 cells assessed as cell shrinkage at 50 mg/kg via oral gavage for 17 days by H&E staining based analysis	Mus musculus	2	ALA4406863	organism-based format	Scientific Literature
10.	ALA4409567	Functional	Induction of apoptosis in BALB/c mouse xenografted with CT26 cells assessed as nuclear chromatin condensation at 50 mg/kg via oral gavage for 17 days by H&E staining based analysis	Mus musculus	2	ALA4406863	organism-based format	Scientific Literature
11.	ALA4409568	Functional	Induction of apoptosis in BALB/c mouse xenografted with CT26 cells assessed as nuclear chromatin margination at 50 mg/kg via oral gavage for 17 days by H&E staining based analysis	Mus musculus	2	ALA4406863	organism-based format	Scientific Literature
12.	ALA4409575	Functional	Effect on IDO1 expression in IFN-gamma-stimulated human HeLa cells at 3 times IDO1 IC50 for 24 hrs by western blot analysis	Homo sapiens	5	ALA4406863	cell-based format	Scientific Literature