#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4409553	B	Inhibition of IFN-gamma-induced human TDO2 transfected in HeLa cells at 10 times IDO1 IC50 concentration using L-tryptophan as substrate incubated for 24 hrs relative to control	Homo sapiens	6		cell-based format	Scientific Literature
2.	ALA4409554	B	Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 24 hrs	Homo sapiens	37		cell-based format	Scientific Literature
3.	ALA4409555	A	Cytotoxicity against human HeLa cells assessed as survival rate at 30 uM incubated for 24 hrs by MTT assay relative to control	Homo sapiens	36		cell-based format	Scientific Literature
4.	ALA4409556	B	Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production at 30 uM using L-tryptophan as substrate incubated for 24 hrs relative to control	Homo sapiens	36		cell-based format	Scientific Literature
5.	ALA4409558	B	Reversal of IDO1-mediated immunosuppression in mouse CT26 co-cultured with T-cells assessed as increase in T cell proliferation measured after 48 hrs by MTT assay	Mus musculus	3		assay format	Scientific Literature
6.	ALA4409559	B	Reversal of IDO1-mediated immunosuppression in mouse CT26 co-cultured with T-cells assessed as increase in IFN-gamma production measured after 48 hrs by ELISA	Mus musculus	1		assay format	Scientific Literature
7.	ALA4409560	B	Reversal of IDO1-mediated immunosuppression in mouse CT26 co-cultured with T-cells assessed as ConA- stimulated differentiation of Treg cells at 0.3 uM measured after 48 hrs by FOXP3-APC based flow cytometry analysis (Rvb = 11.4 %)	Mus musculus	3		assay format	Scientific Literature
8.	ALA4409561	F	Antitumor activity against mouse CT26 cells xenografted in BALB/c mouse assessed as decrease in tumour growth at 50 mg/kg, po via gavage for 17 days by vernier caliper method	Mus musculus	2		organism-based format	Scientific Literature
9.	ALA4409566	F	Induction of apoptosis in BALB/c mouse xenografted with CT26 cells assessed as cell shrinkage at 50 mg/kg via oral gavage for 17 days by H&E staining based analysis	Mus musculus	2		organism-based format	Scientific Literature
10.	ALA4409567	F	Induction of apoptosis in BALB/c mouse xenografted with CT26 cells assessed as nuclear chromatin condensation at 50 mg/kg via oral gavage for 17 days by H&E staining based analysis	Mus musculus	2		organism-based format	Scientific Literature
11.	ALA4409568	F	Induction of apoptosis in BALB/c mouse xenografted with CT26 cells assessed as nuclear chromatin margination at 50 mg/kg via oral gavage for 17 days by H&E staining based analysis	Mus musculus	2		organism-based format	Scientific Literature
12.	ALA4409575	F	Effect on IDO1 expression in IFN-gamma-stimulated human HeLa cells at 3 times IDO1 IC50 for 24 hrs by western blot analysis	Homo sapiens	5		cell-based format	Scientific Literature