# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4405109 | B | Inhibition of AIMP2 DX2 isoform (unknown origin) expressed in human A549 cells incubated for 4 hrs by luciferase reporter gene assay | Homo sapiens | 3 | ALA4402586 | cell-based format | Scientific Literature | |
2. | ALA4405110 | F | Growth inhibition of human NCI-H460 cells incubated for 72 hrs by MTT assay | Homo sapiens | 2 | ALA4402586 | cell-based format | Scientific Literature | |
3. | ALA4405111 | F | Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay | Homo sapiens | 2 | ALA4402586 | cell-based format | Scientific Literature | |
4. | ALA4405112 | F | Growth inhibition of human Calu6 cells incubated for 72 hrs by MTT assay | Homo sapiens | 2 | ALA4402586 | cell-based format | Scientific Literature | |
5. | ALA4405113 | F | Growth inhibition of human NCI-H1299 cells incubated for 72 hrs by MTT assay | Homo sapiens | 2 | ALA4402586 | cell-based format | Scientific Literature | |
6. | ALA4405114 | B | Binding affinity to AIMP2 DX2 isoform (unknown origin) | Homo sapiens | 2 | ALA4402586 | single protein format | Scientific Literature | |
7. | ALA4405115 | A | Growth inhibition of human WI26 cells incubated for 72 hrs by MTT assay | Homo sapiens | 2 | ALA4402586 | assay format | Scientific Literature | |
8. | ALA4405116 | B | Induction of AIMP2 DX2 isoform degradation in human NCI-H460 cells at 1.2 to 10 uM by immunoblotting analysis | Homo sapiens | 2 | ALA4402586 | cell-based format | Scientific Literature | |
9. | ALA4405117 | A | Effect on AIMP2 DX2 isoform mRNA expression in human NCI-H460 cells at 1.2 to 10 uM by RT-PCR analysis | Homo sapiens | 2 | ALA4402586 | cell-based format | Scientific Literature | |
10. | ALA4405118 | B | Binding affinity to AIMP2 DX2 isoform (unknown origin) assessed as decrease in emission at 335 nm by measuring protein fluorescence quenching fluorescence-based equilibrium binding assay | Homo sapiens | 2 | ALA4402586 | single protein format | Scientific Literature | |
11. | ALA4405119 | F | Antitumor activity against human NCI-H460 cells xenografted in BALB/c mouse assessed as decrease in tumor size at 40 mg/kg, ip dosed every other day for 13 days | Homo sapiens | 2 | ALA4402586 | organism-based format | Scientific Literature | |
12. | ALA4405120 | F | Antitumor activity against human NCI-H460 cells xenografted in BALB/c mouse assessed as decrease in tumor volume at 40 mg/kg, ip dosed every other day for 13 days | Homo sapiens | 2 | ALA4402586 | organism-based format | Scientific Literature | |
13. | ALA4405121 | T | Toxicity in BALB/c mouse xenografted with human NCI-H460 cells at 40 mg/kg, ip dosed every other day for 13 days | Mus musculus | 1 | ALA4402586 | organism-based format | Scientific Literature | |
14. | ALA4405122 | F | Inhibition of tumor AIMP2-DX2 expression in BALB/c mouse xenografted with human NCI-H460 cells at 40 mg/kg, ip dosed every other day for 13 days by SDS-PAGE and Western blotting analysis | Mus musculus | 2 | ALA4402586 | organism-based format | Scientific Literature | |
15. | ALA4405123 | A | Effect on tumor AIMP2 expression in BALB/c mouse xenografted with human NCI-H460 cells at 40 mg/kg, ip dosed every other day for 13 days by SDS-PAGE and Western blotting analysis | Mus musculus | 2 | ALA4402586 | organism-based format | Scientific Literature | |
16. | ALA4405124 | T | Toxicity in BALB/c mouse xenografted with human NCI-H460 cells assessed effect on body weight at 40 mg/kg, ip dosed every other day for 13 days | Mus musculus | 2 | ALA4402586 | organism-based format | Scientific Literature | |
17. | ALA4405125 | A | Drug level in tumor of BALB/c mouse xenografted with human NCI-H460 cells assessed effect on body weight at 40 mg/kg, ip dosed every other day for 13 days | Mus musculus | 2 | ALA4402586 | organism-based format | Scientific Literature |