# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4402766 | Binding | Selectivity index, ratio of Ki for displacement of [3H]CGP12177 from human beta2 adrenoceptor expressed in CHO cell membranes to Ki for displacement of [3H]CGP12177 from mouse beta1 adrenoceptor expressed in HEK293T cell membranes | 16 | ALA4402511 | cell-based format | Scientific Literature | ||
2. | ALA4402767 | Binding | Displacement of [3H]CGP12177 from mouse beta1 adrenoceptor expressed in HEK293T cell membranes | Mus musculus | 16 | ALA4402511 | cell-based format | Scientific Literature | |
3. | ALA4402768 | Binding | Displacement of [3H]CGP12177 from human beta2 adrenoceptor expressed in CHO cell membranes | Homo sapiens | 16 | ALA4402511 | cell-based format | Scientific Literature | |
4. | ALA4402770 | Binding | Displacement of [3H]CGP12177 from mouse beta1 adrenoceptor I2.64C mutant expressed in HEK293T cell membranes | Mus musculus | 16 | ALA4402511 | cell-based format | Scientific Literature | |
5. | ALA4402771 | Binding | Displacement of [3H]CGP12177 from human beta2 adrenoceptor H2.64C mutant expressed in HEK293T cell membranes | Homo sapiens | 16 | ALA4402511 | cell-based format | Scientific Literature | |
6. | ALA4402783 | Binding | Covalent binding affinity to mouse beta1 adrenoceptor I2.64C mutant expressed in HEK293T cell membranes assessed as covalent blockage of binding site at 1 uM measured after 120 mins by [3H]CGP12177 binding based radioligand depletion assay relative to control | Mus musculus | 2 | ALA4402511 | cell-based format | Scientific Literature | |
7. | ALA4402784 | Binding | Covalent binding affinity to human beta2 adrenoceptor H2.64C mutant expressed in HEK293T cell membranes assessed as covalent blockage of binding site at 1 uM measured after 120 mins by [3H]CGP12177 binding based radioligand depletion assay relative to control | Homo sapiens | 2 | ALA4402511 | cell-based format | Scientific Literature |