# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4364954 | Functional | Antiviral activity against pseudotyped Enterovirus A71 infected in human muscular rhabdomyosarcoma cells treated prior to viral infection and measured after 24 hrs by luminescence method | Enterovirus A71 | 32 | ALA4364253 | organism-based format | Scientific Literature | |
2. | ALA4364955 | ADME | Cytotoxicity against human RD cells at 100 uM after 24 hrs by WST-1 assay relative to control | Homo sapiens | 32 | ALA4364253 | cell-based format | Scientific Literature | |
3. | ALA4364957 | Binding | Reversible inhibition of Enterovirus 71 3C protease assessed as overall inhibition constant using NMA-IEALFQGPPK(DNP)FR as substrate pre-incubated for 30 mins followed by substrate addition and measured over 30 mins by fluorescence method | Enterovirus A71 | 28 | ALA4364253 | assay format | Scientific Literature |