#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4361668	Binding	Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells at 10 uM using casein as substrate incubated for 60 mins in presence of [33P]-ATP by radiometric assay relative to control	Homo sapiens	16	ALA4359846	cell-based format	Scientific Literature
2.	ALA4361669	Binding	Inhibition of human recombinant untagged p38alpha expressed in Escherichia coli at 10 uM using ATF2 as substrate incubated for 60 mins in presence of [33P]-ATP by radiometric assay relative to control	Homo sapiens	22	ALA4359846	assay format	Scientific Literature
3.	ALA4361670	Binding	Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-ATP by radiometric assay	Homo sapiens	16	ALA4359846	cell-based format	Scientific Literature
4.	ALA4361671	Binding	Inhibition of human recombinant untagged p38alpha expressed in Escherichia coli using ATF2 as substrate incubated for 60 mins in presence of [33P]-ATP by radiometric assay	Homo sapiens	16	ALA4359846	assay format	Scientific Literature
5.	ALA4361672	Binding	Selectivity index, ratio of IC50 for human recombinant untagged p38alpha expressed in Escherichia coli to IC50 for human recombinant GST-tagged ALK5 expressed in Sf9 insect cells	Homo sapiens	16	ALA4359846	cell-based format	Scientific Literature
6.	ALA4361673	ADME	Cytotoxicity against human LX2 cells assessed as reduction in cell viability at 4 to 100 uM incubated for 3 hrs by MTT assay	Homo sapiens	2	ALA4359846	cell-based format	Scientific Literature
7.	ALA4361674	Binding	Inhibition of ALK5 in human LX2 cells assessed as reduction in TGFbeta-induced collagen 1 production pretreated for 1 hr followed by TGFbeta addition and measured after 12 hrs by DAPI staining based immunocytochemistry analysis by confocal laser scanning microscopic method	Homo sapiens	2	ALA4359846	cell-based format	Scientific Literature
8.	ALA4361675	Binding	Inhibition of ALK5 in human LX2 cells assessed as reduction in TGFbeta-induced alphaSMA production pretreated for 1 hr followed by TGFbeta addition and measured after 12 hrs by DAPI staining based immunocytochemistry analysis by confocal laser scanning microscopic method	Homo sapiens	2	ALA4359846	cell-based format	Scientific Literature
9.	ALA4361678	Binding	Inhibition of ALK5 in human LX2 cells assessed as reduction in TGFbeta-induced collagen 1 protein expression at 1.25 to 5 uM pretreated for 1 hr followed by TGFbeta addition and measured after 12 hrs by Western blot analysis	Homo sapiens	2	ALA4359846	cell-based format	Scientific Literature
10.	ALA4361679	Binding	Inhibition of ALK5 in human LX2 cells assessed as reduction in TGFbeta-induced alphaSMA protein expression at 1.25 to 5 uM pretreated for 1 hr followed by TGFbeta addition and measured after 12 hrs by Western blot analysis	Homo sapiens	2	ALA4359846	cell-based format	Scientific Literature
11.	ALA4361680	Binding	Inhibition of ALK5 in human LX2 cells assessed as reduction in TGFbeta-induced ACTA2 mRNA expression at 1.25 to 5 uM pretreated for 1 hr followed by TGFbeta addition and measured after 12 hrs by RT-PCR analysis	Homo sapiens	2	ALA4359846	cell-based format	Scientific Literature
12.	ALA4361681	Binding	Inhibition of ALK5 in human LX2 cells assessed as reduction in TGFbeta-induced COL1A1 mRNA expression at 1.25 to 5 uM pretreated for 1 hr followed by TGFbeta addition and measured after 12 hrs by RT-PCR analysis	Homo sapiens	2	ALA4359846	cell-based format	Scientific Literature