| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4428628 | B | Inhibition of N-terminal FLAG-tagged and C-terminal SBP-tagged Staphylococcus aureus recombination UppS assessed as reduction in IPP condensation to growing prenyl chain by measuring pyrophosphate production incubated for 30 mins | Staphylococcus aureus | 2 | assay format | Scientific Literature | ||
| 2. | ALA4428629 | B | Binding affinity to N-terminal FLAG-tagged and C-terminal SBP-tagged Staphylococcus aureus recombinant UppS expressed in Escherichia coli by affinity selection based ELT screen assay | Staphylococcus aureus | 2 | assay format | Scientific Literature | ||
| 3. | ALA4428630 | B | Inhibition of hexa-histidine tagged Acinetobacter baumannii UppS expressed in Escherichia coli assessed as reduction in IPP condensation to growing prenyl chain by measuring pyrophosphate production | Acinetobacter baumannii | 2 | assay format | Scientific Literature | ||
| 4. | ALA4428631 | B | Inhibition of hexa-histidine tagged Klebsiella pneumoniae UppS expressed in Escherichia coli assessed as reduction in IPP condensation to growing prenyl chain by measuring pyrophosphate production | Klebsiella pneumoniae | 2 | assay format | Scientific Literature | ||
| 5. | ALA4428632 | B | Inhibition of hexa-histidine tagged Pseudomonas aeruginosa UppS expressed in Escherichia coli assessed as reduction in IPP condensation to growing prenyl chain by measuring pyrophosphate production incubated for 30 mins | Pseudomonas aeruginosa | 2 | assay format | Scientific Literature | ||
| 6. | ALA4428633 | B | Binding affinity to N-terminal FLAG-tagged and C-terminal SBP-tagged Staphylococcus aureus recombination UppS assessed change in melting temperature at 10 uM by SYPRO Orange based assay | Staphylococcus aureus | 2 | assay format | Scientific Literature | ||
| 7. | ALA4428634 | F | Antibacterial activity against Staphylococcus aureus OXFORD incubated for 18 to 24 hrs by broth microdilution method | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 8. | ALA4428635 | F | Antibacterial activity against Staphylococcus aureus WCUH29 incubated for 18 to 24 hrs by broth microdilution method | Staphylococcus aureus | 4 | organism-based format | Scientific Literature | ||
| 9. | ALA4428636 | F | Antibacterial activity against Streptococcus pneumoniae 1629 incubated for 18 to 24 hrs by broth microdilution method | Streptococcus pneumoniae | 4 | organism-based format | Scientific Literature | ||
| 10. | ALA4428637 | F | Antibacterial activity against Streptococcus pneumoniae Ery2 incubated for 18 to 24 hrs by broth microdilution method | Streptococcus pneumoniae | 4 | organism-based format | Scientific Literature | ||
| 11. | ALA4428638 | F | Antibacterial activity against Streptococcus pyogenes 1307006P incubated for 18 to 24 hrs by broth microdilution method | Streptococcus pyogenes | 4 | organism-based format | Scientific Literature | ||
| 12. | ALA4428639 | F | Antibacterial activity against Moraxella catarrhalis 1502 incubated for 18 to 24 hrs by broth microdilution method | Moraxella catarrhalis | 4 | organism-based format | Scientific Literature | ||
| 13. | ALA4428640 | F | Antibacterial activity against Haemophilus influenzae H128 incubated for 18 to 24 hrs by broth microdilution method | Haemophilus influenzae | 4 | organism-based format | Scientific Literature | ||
| 14. | ALA4428641 | F | Antibacterial activity against Haemophilus influenzae H128 deficient in AcrA incubated for 18 to 24 hrs by broth microdilution method | Haemophilus influenzae | 4 | organism-based format | Scientific Literature | ||
| 15. | ALA4428642 | F | Antibacterial activity against Klebsiella pneumoniae 1161486a deficient in tolC incubated for 18 to 24 hrs by broth microdilution method | Klebsiella pneumoniae | 4 | organism-based format | Scientific Literature | ||
| 16. | ALA4428643 | F | Antibacterial activity against Escherichia coli 120 deficient in AcrAB incubated for 18 to 24 hrs by broth microdilution method | Escherichia coli | 4 | organism-based format | Scientific Literature | ||
| 17. | ALA4428644 | F | Antibacterial activity against Pseudomonas aeruginosa PAO322 deficient in MexA/B/C/D/E/F incubated for 18 to 24 hrs by broth microdilution method | Pseudomonas aeruginosa | 4 | organism-based format | Scientific Literature | ||
| 18. | ALA4428645 | F | Antibacterial activity against Acinetobacter baumannii ACM1010 incubated for 18 to 24 hrs by broth microdilution method | Acinetobacter baumannii | 4 | organism-based format | Scientific Literature | ||
| 19. | ALA4428646 | F | Antibacterial activity against Staphylococcus aureus RN4220 transfected with pYH4 in absence of anhydrotetracycline incubated for 18 to 24 hrs by broth microdilution method | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA4428647 | F | Antibacterial activity against Staphylococcus aureus RN4220 transfected with pYH4 in presence of anhydrotetracycline incubated for 18 to 24 hrs by broth microdilution method | Staphylococcus aureus | 2 | organism-based format | Scientific Literature |
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