| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4386108 | Binding | Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysis | Cavia porcellus | 30 | ALA4385605 | cell membrane format | Scientific Literature | |
| 2. | ALA4386109 | Binding | Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes incubated for 120 mins in the presence of sigma1 receptor ligand (+)-pentazocine by scintillation counting method | Rattus norvegicus | 26 | ALA4385605 | cell membrane format | Scientific Literature | |
| 3. | ALA4386111 | Binding | Selectivity ratio of Ki for displacement of [3H]DTG from sigma2 receptor in rat liver membranes to Ki for displacement of (+)-[3H]pentazocine from sigma 1 receptor in guinea pig brain cortex membranes | 27 | ALA4385605 | cell membrane format | Scientific Literature | ||
| 4. | ALA4386112 | Binding | Displacement of [3H](+)-pentazocine from sigma 1 receptor in human RPMI8226 cell membranes incubated for 2 hrs under shaking by scintillation counting analysis | Homo sapiens | 4 | ALA4385605 | cell-based format | Scientific Literature | |
| 5. | ALA4386114 | Binding | Displacement of [3H]DAMGO from mu opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysis | Cavia porcellus | 24 | ALA4385605 | cell membrane format | Scientific Literature | |
| 6. | ALA4386116 | Binding | Displacement of [3H]DPDPE from delta opioid receptor in rat membranes after 120 mins by scintillation counting analysis | Rattus norvegicus | 22 | ALA4385605 | cell membrane format | Scientific Literature | |
| 7. | ALA4386117 | Binding | Displacement of [3H]U69,593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation counting analysis | Cavia porcellus | 18 | ALA4385605 | cell membrane format | Scientific Literature | |
| 8. | ALA4386118 | Binding | Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in human RT4 cell membranes incubated for 120 mins in the presence of sigma1 receptor ligand (+)-pentazocine by scintillation counting method | Homo sapiens | 28 | ALA4385605 | cell-based format | Scientific Literature | |
| 9. | ALA4386124 | Binding | Displacement of [3H]-(+)-MK-801 from PCP binding site of NMDA receptor in pig brain cortex membranes up to 1 uM after 120 mins by scintillation counting analysis | Sus scrofa | 8 | ALA4385605 | cell membrane format | Scientific Literature | |
| 10. | ALA4386125 | ADME | Inhibition of recombinant human CYP3A4 at 1 uM by fluorescence assay | Homo sapiens | 4 | ALA4385605 | single protein format | Scientific Literature | |
| 11. | ALA4386126 | ADME | Inhibition of recombinant human CYP2D6 at 1 uM by fluorescence assay relative to control | Homo sapiens | 4 | ALA4385605 | single protein format | Scientific Literature | |
| 12. | ALA4386127 | ADME | Cytotoxicity against human HepG2 cells at 1 to 100 uM incubated for 20 hrs under serum free condition by MTT assay | Homo sapiens | 4 | ALA4385605 | cell-based format | Scientific Literature | |
| 13. | ALA4386128 | ADME | Cytotoxicity against human HepG2 cells at 1 to 100 uM incubated for 20 hrs under serum free condition by neutral red uptake assay | Homo sapiens | 4 | ALA4385605 | cell-based format | Scientific Literature | |
| 14. | ALA4386129 | ADME | Inhibition of recombinant human CYP1A2 at 1 uM by fluorescence assay | Homo sapiens | 4 | ALA4385605 | single protein format | Scientific Literature | |
| 15. | ALA4386130 | ADME | Inhibition of recombinant human CYP2C9 at 1 uM by fluorescence assay | Homo sapiens | 4 | ALA4385605 | single protein format | Scientific Literature | |
| 16. | ALA4386131 | ADME | Inhibition of recombinant human CYP2C19 at 1 uM by fluorescence assay | Homo sapiens | 4 | ALA4385605 | single protein format | Scientific Literature | |
| 17. | ALA4386132 | ADME | Metabolic stability in human liver microsomes assessed as parent compound remaining at 1 uM in the presence of NADPH regenerating system after 60 mins by UPLC/MS analysis | Homo sapiens | 4 | ALA4385605 | microsome format | Scientific Literature | |
| 18. | ALA4386134 | Binding | Binding affinity to noradrenaline transporter (unknown origin) at 1 uM | Homo sapiens | 4 | ALA4385605 | single protein format | Scientific Literature | |
| 19. | ALA4386135 | Binding | Binding affinity to dopamine transporter (unknown origin) at 1 uM | Homo sapiens | 4 | ALA4385605 | single protein format | Scientific Literature | |
| 20. | ALA4386136 | Binding | Binding affinity to alpha 1a adrenergic receptor (unknown origin) at 1 uM relative to control | Homo sapiens | 4 | ALA4385605 | single protein format | Scientific Literature |
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