# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4394697 | B | Inhibition of recombinant human N-terminal GST-tagged CHK1 (M1 to T476 residues) expressed in baculovirus infected insect cells using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay | Homo sapiens | 40 | ALA4393675 | cell-based format | Scientific Literature | |
2. | ALA4394698 | B | Inhibition of recombinant human N-terminal GST-tagged CHK2 (M1 to L543 residues) expressed in baculovirus infected insect cells using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | cell-based format | Scientific Literature | |
3. | ALA4394699 | B | Inhibition of AMPK alpha2beta1gamma1 (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | assay format | Scientific Literature | |
4. | ALA4394700 | B | Inhibition of AMPKalpha1beta1gamma1 (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | protein complex format | Scientific Literature | |
5. | ALA4394701 | B | Inhibition of recombinant human full length N-terminal His-tagged PIM1 (1 to 313 residues) expressed in baculovirus expression system using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | assay format | Scientific Literature | |
6. | ALA4394702 | B | Inhibition of PIM3 (unknown origin) incubated for 60 mins using biotin-labelled STK substrate-1 as substrate by HTRF assay | Homo sapiens | 2 | ALA4393675 | single protein format | Scientific Literature | |
7. | ALA4394703 | B | Inhibition of CDK1 (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | single protein format | Scientific Literature | |
8. | ALA4394704 | B | Inhibition of CDK2 (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | single protein format | Scientific Literature | |
9. | ALA4394705 | B | Inhibition of p70S6K (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | single protein format | Scientific Literature | |
10. | ALA4394706 | B | Inhibition of PKCepsilon (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | single protein format | Scientific Literature | |
11. | ALA4394707 | B | Inhibition of PKA (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | assay format | Scientific Literature | |
12. | ALA4394708 | B | Inhibition of recombinant human C-terminal His-tagged FLT3 (M1 to N541 residues) expressed in HEK293 cells using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | cell-based format | Scientific Literature | |
13. | ALA4394709 | B | Inhibition of BLK (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | single protein format | Scientific Literature | |
14. | ALA4394710 | B | Inhibition of LCK (unknown origin) incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | single protein format | Scientific Literature | |
15. | ALA4394711 | B | Inhibition of LYN (unknown origin) incubated for 60 mins by HTRF assay | Homo sapiens | 2 | ALA4393675 | single protein format | Scientific Literature | |
16. | ALA4394724 | F | Antitumor activity against human Z138 cells xenografted in intravenously dosed nu/nu mouse assessed as tumor growth, iv administered 5 times a week for 3 weeks and measured twice per week by caliper method | Homo sapiens | 1 | ALA4393675 | organism-based format | Scientific Literature | |
17. | ALA4394725 | F | Antitumor activity against human Z138 cells xenografted in nu/nu mouse assessed as inhibition in tumor growth at 10 mg/kg, iv administered 5 times a week for 3 weeks and measured twice per week by caliper method relative to control | Homo sapiens | 1 | ALA4393675 | organism-based format | Scientific Literature | |
18. | ALA4394726 | F | Antitumor activity against human Z138 cells xenografted in nu/nu mouse assessed as inhibition in tumor growth at 20 mg/kg, iv administered 5 times a week for 3 weeks and measured twice per week by caliper method relative to control | Homo sapiens | 1 | ALA4393675 | organism-based format | Scientific Literature | |
19. | ALA4394727 | T | Toxicity in human Z138 cells xenografted in nu/nu mouse assessed as change in body weight at 10 to 20 mg/kg, iv administered 5 times a week for 3 weeks and measured twice per week | Mus musculus | 1 | ALA4393675 | organism-based format | Scientific Literature | |
20. | ALA4394728 | T | Toxicity in human Z138 cells xenografted in nu/nu mouse assessed as adverse effect at 10 to 20 mg/kg, iv administered 5 times a week for 3 weeks and measured twice per week | Mus musculus | 1 | ALA4393675 | organism-based format | Scientific Literature |