| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4480899 | Binding | Inhibition of recombinant human N-terminal GST-tagged CDK4 (S4 to E303 residues)/Cyclin D1 (Q4 to I295 residues) expressed in sf9 cells at 10 uM using RBCTF as substrate measured after 1 hr by ADP-glo luminescence assay relative to control | Homo sapiens | 47 | ALA4480390 | cell-based format | Scientific Literature | |
| 2. | ALA4480900 | Binding | Inhibition of human full length N-terminal GST-fused CDK2 (M1 to L298 residues)/human full length Cyclin-A2 (M1 to L432 residues) expressed in Sf9 cells at 10 uM using histone H1 as substrate measured after 1 hr by ADP-glo luminescence assay relative to control | Homo sapiens | 5 | ALA4480390 | cell-based format | Scientific Literature | |
| 3. | ALA4480901 | Binding | Inhibition of recombinant human N-terminal GST/His6-tagged CDK1 (M1 to M297 residues)/CyclinB1 (M1 to V433 residues) expressed in Sf9 insect cells at 10 uM using RBCTF as substrate measured after 1 hr by ADP-glo luminescence assay relative to control | Homo sapiens | 5 | ALA4480390 | cell-based format | Scientific Literature | |
| 4. | ALA4480902 | Binding | Inhibition of N-terminal GST-HIS6 fusion protein tagged human full length CDK9 (M1 to F372 residues)/N-terminal HIS6-fused human Cyclin-T1 (M1 to K726 residues) expressed in Sf9 cells at 10 uM using RBCTF as substrate measured after 1 hr by ADP-glo luminescence assay relative to control | Homo sapiens | 5 | ALA4480390 | cell-based format | Scientific Literature | |
| 5. | ALA4480903 | Binding | Inhibition of CDK6/cyclin D1 (unknown origin) at 10 uM using RBER-CHKtide as substrate measured after 1 hr by ADP-glo luminescence assay relative to control | Homo sapiens | 5 | ALA4480390 | protein complex format | Scientific Literature | |
| 6. | ALA4480904 | Binding | Inhibition of recombinant human N-terminal GST-tagged CDK4 (S4 to E303 residues)/Cyclin D1 (Q4 to I295 residues) expressed in sf9 cells using RBCTF as substrate measured after 1 hr by ADP-glo luminescence assay | Homo sapiens | 5 | ALA4480390 | cell-based format | Scientific Literature | |
| 7. | ALA4480905 | Binding | Inhibition of human full length N-terminal GST-fused CDK2 (M1 to L298 residues)/human full length Cyclin-A2 (M1 to L432 residues) expressed in Sf9 cells using histone H1 as substrate measured after 1 hr by ADP-glo luminescence assay | Homo sapiens | 5 | ALA4480390 | cell-based format | Scientific Literature | |
| 8. | ALA4480906 | Binding | Inhibition of recombinant human N-terminal GST/His6-tagged CDK1 (M1 to M297 residues)/CyclinB1 (M1 to V433 residues) expressed in Sf9 insect cells using RBCTF as substrate measured after 1 hr by ADP-glo luminescence assay | Homo sapiens | 5 | ALA4480390 | cell-based format | Scientific Literature | |
| 9. | ALA4480907 | Binding | Inhibition of N-terminal GST-HIS6 fusion protein tagged human full length CDK9 (M1 to F372 residues)/N-terminal HIS6-fused human Cyclin-T1 (M1 to K726 residues) expressed in Sf9 cells using RBCTF as substrate measured after 1 hr by ADP-glo luminescence assay | Homo sapiens | 5 | ALA4480390 | cell-based format | Scientific Literature | |
| 10. | ALA4480908 | Binding | Inhibition of CDK6/cyclin D1 (unknown origin) using RBER-CHKtide as substrate measured after 1 hr by ADP-glo luminescence assay | Homo sapiens | 5 | ALA4480390 | protein complex format | Scientific Literature | |
| 11. | ALA4480909 | ADME | Inhibition of recombinant human CYP1A1 expressed in baker's yeast-derived microsomes using 7-ethoxyresorufin as substrate by fluorescence assay | Homo sapiens | 4 | ALA4480390 | microsome format | Scientific Literature | |
| 12. | ALA4480910 | ADME | Inhibition of recombinant human CYP1A2 expressed in baker's yeast-derived microsomes using 3-cyano-7-ethoxycoumarin as substrate by fluorescence assay | Homo sapiens | 4 | ALA4480390 | microsome format | Scientific Literature | |
| 13. | ALA4480911 | Binding | Inhibition of recombinant human CYP1B1 expressed in baker's yeast-derived microsomes using 7-ethoxyresorufin as substrate by fluorescence assay | Homo sapiens | 4 | ALA4480390 | microsome format | Scientific Literature | |
| 14. | ALA4480912 | Binding | Inhibition of porcine tubulin polymerization at 5 uM incubated for 1 min by fluorescence based assay | Sus scrofa | 4 | ALA4480390 | protein format | Scientific Literature | |
| 15. | ALA4480914 | Binding | Inhibition of porcine tubulin polymerization incubated for 1 min by fluorescence based assay | Sus scrofa | 1 | ALA4480390 | protein format | Scientific Literature | |
| 16. | ALA4480915 | Functional | Growth inhibition of human A549 cells measured after 72 hrs by propidium iodide staining based fluorescence assay | Homo sapiens | 5 | ALA4480390 | cell-based format | Scientific Literature | |
| 17. | ALA4480916 | Functional | Growth inhibition of human Calu1 cells measured after 72 hrs by propidium iodide staining based fluorescence assay | Homo sapiens | 5 | ALA4480390 | cell-based format | Scientific Literature | |
| 18. | ALA4480917 | Functional | Growth inhibition of human MDA-MB-468 cells measured after 72 hrs by propidium iodide staining based fluorescence assay | Homo sapiens | 5 | ALA4480390 | cell-based format | Scientific Literature | |
| 19. | ALA4480918 | Functional | Growth inhibition of human T47D cells measured after 72 hrs by propidium iodide staining based fluorescence assay | Homo sapiens | 5 | ALA4480390 | cell-based format | Scientific Literature | |
| 20. | ALA4480919 | Functional | Cell cycle arrest in human T47D cells assessed as ratio of G1 to S phase at 0.75 uM measured after 18 hrs by propidium iodide staining based flow cytometry (Rvb = 2.65 No_unit) | Homo sapiens | 1 | ALA4480390 | cell-based format | Scientific Literature |
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