# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4387487 | B | Inhibition of human TRPV4 expressed in HEK293 cells assessed as reduction in Ca2+ influx incubated for 30 mins by Fluo4-AM dye based | Homo sapiens | 29 | ALA4385652 | cell-based format | Scientific Literature | |
2. | ALA4387488 | P | Aqueous solubility in pH 6.8 JP2 buffer incubated for 24 hrs by HPLC analysis | 29 | ALA4385652 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4387489 | P | Lipophilicity, log D of the compound in 1-Octanol-phosphate buffer at pH 7.4 by LC-MS/MS analysis | 29 | ALA4385652 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4387490 | B | Inhibition of rat TRPV4 expressed in HEK293 cells assessed as reduction in Ca2+ influx incubated for 30 mins by Fluo4-AM dye based | Rattus norvegicus | 4 | ALA4385652 | cell-based format | Scientific Literature | |
5. | ALA4387491 | A | Intrinsic clearance in pooled human liver microsomes at 0.2 uM pre-incubated 15 mins before NADPH addition and measured up to 45 mins by LC-MS/MS and UPLC analysis | Homo sapiens | 3 | ALA4385652 | microsome format | Scientific Literature | |
6. | ALA4387492 | A | Intrinsic clearance in pooled rat liver microsomes at 0.2 uM pre-incubated 15 mins before NADPH addition and measured up to 45 mins by LC-MS/MS and UPLC analysis | Rattus norvegicus | 3 | ALA4385652 | microsome format | Scientific Literature |