| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4423881 | B | Inhibition of TEAD (unknown origin) expressed in human HeLa cells at 100 uM after 6 hrs by nanoluciferase reporter gene assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA4423882 | A | Cytotoxicity against human HeLa cells assessed as reduction in cell viability by measuring ethidium homodimer-1 uptake at 100 uM preincubated for 10 mins followed by ethidium homodimer-1 addition measured after 10 mins by fluorescence assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4423883 | B | Inhibition of human HEK293 cell lysate derived YAP interaction with recombinant GST-tagged human TEAD1 (194 to 411 residues) expressed in Escherichia coli soluBL21 at 200 uM after 18 hrs by Western blot analysis | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 4. | ALA4423884 | B | Inhibition of GFP-tagged YAP1 (unknown origin) interaction with myc-tagged human TEAD1 expressed in human HeLa cells by measuring GFP-Trap at 200 uM incubated for 30 mins with myc-tagged human TEAD1 lysate followed by GFP-tagged YAP1 lysate addition measured after 30 mins by Western blot based immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4423885 | B | Inhibition of GFP-tagged YAP1 (unknown origin) interaction with myc-tagged human TEAD1 expressed in human HeLa cells by measuring myc-TRAP at 200 uM incubated for 30 mins with myc-tagged human TEAD1 lysate followed by GFP-tagged YAP1 lysate addition measured after 30 mins by Western blot based immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4423886 | B | Inhibition of NL-tagged YAP (unknown origin) interaction with myc-tagged human TEAD1 preincubated for 1 hr followed by NL-tagged YAP addition by NanoGlo assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4423887 | B | Inhibition of TEAD in human HeLa cells assessed as reduction in CCN1 m-RNA expression incubated for 2 hrs followed by compound wash out and re-treatment for 4 hrs by by NanoGlo assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4423888 | B | Inhibition of TEAD in human HeLa cells assessed as reduction in CTGF m-RNA expression incubated for 2 hrs followed by compound wash out and re-treatment for 4 hrs by by NanoGlo assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4423889 | B | Inhibition of TEAD in rat VSMC assessed as reduction in CCN1 m-RNA expression incubated for 2 hrs followed by compound wash out and re-treatment for 4 hrs by by NanoGlo assay | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
| 10. | ALA4423890 | B | Inhibition of TEAD in rat VSMC assessed as reduction in CTGF m-RNA expression incubated for 2 hrs followed by compound wash out and re-treatment for 4 hrs by by NanoGlo assay | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
| 11. | ALA4423891 | F | Inhibition of TNT1 m-RNA expression in human HeLa cells up to 80 uM incubated for 2 hrs followed by compound wash out and re-treatment for 4 hrs by by NanoGlo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4423892 | F | Inhibition of TNT1 m-RNA expression in rat VSMC up to 80 uM incubated for 2 hrs followed by compound wash out and re-treatment for 4 hrs by by NanoGlo assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4423893 | F | Inhibition of 36B4 m-RNA expression in human HeLa cells up to 80 uM incubated for 2 hrs followed by compound wash out and re-treatment for 4 hrs by by NanoGlo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4423894 | F | Inhibition of 36B4 m-RNA expression in rat VSMC up to 80 uM incubated for 2 hrs followed by compound wash out and re-treatment for 4 hrs by by NanoGlo assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4423895 | F | Antiproliferative activity against rat VSMC assessed as reduction in EdU incorporation after 24 hrs by Hoechst 33342 staining-based fluorescence assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4423896 | F | Antiproliferative activity against human HeLa cells assessed as reduction in EdU incorporation after 24 hrs by Hoechst 33342 staining-based fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4423897 | F | Antimigratory activity in rat VSMC incubated for overnight followed by media replacement and measured every hour for 24 hrs by phase contrast microscopic analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4423898 | F | Antimigratory activity in human HeLa cells incubated for overnight followed by media replacement and measured every hour for 24 hrs by phase contrast microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4423899 | A | Cytotoxicity against human HeLa cells assessed as reduction in cell viability by measuring ethidium homodimer-1 uptake at 60 uM preincubated for 10 mins followed by ethidium homodimer-1 addition measured after 10 mins by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4423900 | B | Inhibition of TEAD (unknown origin) expressed in human HeLa cells after 6 hrs by nanoluciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature |
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