# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4402168 | Functional | Cytotoxicity against human NCI-H23 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature | |
2. | ALA4402169 | Functional | Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature | |
3. | ALA4402170 | Functional | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 2 | ALA4400568 | cell-based format | Scientific Literature | |
4. | ALA4402171 | ADME | Cytotoxicity against human IMR90 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature | |
5. | ALA4402172 | ADME | Cytotoxicity against human QSG7701 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature | |
6. | ALA4402173 | ADME | Cytotoxicity against HEK293A cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature | |
7. | ALA4402174 | Functional | Induction of apoptosis in human A549 cells assessed as cell shrinkage at 3 uM by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 2 | ALA4400568 | cell-based format | Scientific Literature | |
8. | ALA4402175 | Functional | Induction of apoptosis in human A549 cells assessed as nuclear condensation at 3 uM by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 2 | ALA4400568 | cell-based format | Scientific Literature | |
9. | ALA4402176 | Functional | Induction of apoptosis in human A549 cells assessed as decrease in Bcl-2 expression at 3 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4400568 | cell-based format | Scientific Literature | |
10. | ALA4402177 | Functional | Induction of apoptosis in human A549 cells assessed as increase in Bad levels at 3 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4400568 | cell-based format | Scientific Literature | |
11. | ALA4402178 | Functional | Induction of apoptosis in human A549 cells assessed as increase in cleaved caspase-3 expression at 3 uM by Western blot analysis | Homo sapiens | 2 | ALA4400568 | cell-based format | Scientific Literature | |
12. | ALA4402179 | Functional | Induction of apoptosis in human A549 cells assessed as increase in cleaved PARP expression at 3 uM by Western blot analysis | Homo sapiens | 2 | ALA4400568 | cell-based format | Scientific Literature | |
13. | ALA4402180 | Functional | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 3 uM after 3 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 2.73%) | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature | |
14. | ALA4402181 | Functional | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 3 uM after 3 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 4.52%) | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature | |
15. | ALA4402182 | Functional | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 3 uM after 6 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 2.73%) | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature | |
16. | ALA4402183 | Functional | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 3 uM after 6 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 4.52%) | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature | |
17. | ALA4402184 | Functional | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 3 uM after 12 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 2.73%) | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature | |
18. | ALA4402185 | Functional | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 3 uM after 12 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 4.52%) | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature | |
19. | ALA4402186 | Functional | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 3 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 2.73%) | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature | |
20. | ALA4402187 | Functional | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 3 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 4.52%) | Homo sapiens | 3 | ALA4400568 | cell-based format | Scientific Literature |