# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4409815 | A | Cytotoxicity against human TE671 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA4409816 | F | Antiviral activity against Japanese encephalitis virus infected in human TE671 cells assessed as reduction in virus-induced cytopathic effect at 10 to 100 uM treated immediately post-infection measured at 36 hrs post-infection by inverted microscopic analysis | Japanese encephalitis virus | 6 | organism-based format | Scientific Literature | ||
3. | ALA4409817 | F | Antiviral activity against Japanese encephalitis virus infected in human TE671 cells assessed as decline in infected cell apoptotic fraction by measuring proportion of cells at subG1 phase treated immediately post-infection measured at 36 hrs post-infection by PI-staining based flow cytometric analysis | Japanese encephalitis virus | 6 | organism-based format | Scientific Literature | ||
4. | ALA4409818 | F | Antiviral activity against Japanese encephalitis virus infected in human TE671 cells assessed as reduction in virus infectivity by measuring decrease in NS3-positive cells treated immediately post-infection measured after 24 hrs by DAPI-staining based immunofluorescence analysis | Japanese encephalitis virus | 3 | organism-based format | Scientific Literature | ||
5. | ALA4409819 | F | Antiviral activity against Japanese encephalitis virus infected in human TE671 cells assessed as inhibition of intracellular virion production at 10 uM measured at 24 to 48 hrs post-infection by plaque assay | Japanese encephalitis virus | 1 | organism-based format | Scientific Literature | ||
6. | ALA4409820 | F | Antiviral activity against Japanese encephalitis virus infected in human TE671 cells assessed as inhibition of extracellular viral particles production by measuring reduction in virus yield measured after 36 hrs by plaque assay | Japanese encephalitis virus | 3 | organism-based format | Scientific Literature | ||
7. | ALA4409821 | T | Therapeutic index, ratio of CC50 for human TE671 cells to IC50 for antiviral activity against Japanese encephalitis virus infected in human TE671 cells assessed as reduction in virus yield by plaque assay | 3 | cell-based format | Scientific Literature | |||
8. | ALA4409822 | F | Antiviral activity against Japanese encephalitis virus infected in human TE671 cells assessed as reduction in virus entry at early stage by measuring decrease in NS3-positive cells treated immediately after viral infection followed by virus/compound mixture wash-out at 1 hr post-incubation followed by culturing of cells for 24 hrs by DAPI-staining based immunofluorescence analysis | Japanese encephalitis virus | 1 | organism-based format | Scientific Literature | ||
9. | ALA4409824 | F | Inhibition of synthesis of Japanese encephalitis virus RNA genome transfected as EGFP replicon in human TE671 cells assessed as lowered ratio of negative to positive sense strand RNA at 10 uM treated at 1 hr post-transfection and measured at 36 hrs post treatment by RT-PCR analysis | Japanese encephalitis virus | 3 | organism-based format | Scientific Literature | ||
10. | ALA4409825 | F | Antiviral activity against Japanese encephalitis virus infected in human TE671 cells assessed as reduction in virus entry at late stage by measuring decrease in NS3-positive cells treated at 1 hr post-infection followed by virus/compound mixture wash-out at 1 hr post-incubation followed by culturing of cells for 24 hrs by DAPI-staining based immunofluorescence analysis | Japanese encephalitis virus | 1 | organism-based format | Scientific Literature |