#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4401102	B	Inhibition of GST-fused PTP1B catalytic domain (1 to 321 residues) (unknown origin) expressed in Escherichia coli using pNPP as substrate measured after 30 mins by spectrophotometric method	Homo sapiens	23	ALA4400525	assay format	Scientific Literature
2.	ALA4401103	B	Inhibition of TCPTP (unknown origin)	Homo sapiens	6	ALA4400525	single protein format	Scientific Literature
3.	ALA4401104	B	Inhibition of PTP1B A27S mutant (unknown origin)	Homo sapiens	6	ALA4400525	single protein format	Scientific Literature
4.	ALA4401105	B	Inhibition of SHP1 (unknown origin)	Homo sapiens	6	ALA4400525	single protein format	Scientific Literature
5.	ALA4401106	B	Inhibition of SHP2 (unknown origin)	Homo sapiens	6	ALA4400525	single protein format	Scientific Literature
6.	ALA4401107	B	Inhibition of LAR (unknown origin)	Homo sapiens	6	ALA4400525	single protein format	Scientific Literature
7.	ALA4401108	B	Selectivity ratio of IC50 for TCPTP (unknown origin) to IC50 for GST-fused PTP1B catalytic domain (1 to 321 residues) (unknown origin) expressed in Escherichia coli	Homo sapiens	2	ALA4400525	assay format	Scientific Literature
8.	ALA4401109	B	Selectivity ratio of IC50 for SHP1 (unknown origin) to IC50 for GST-fused PTP1B catalytic domain (1 to 321 residues) (unknown origin) expressed in Escherichia coli	Homo sapiens	2	ALA4400525	assay format	Scientific Literature
9.	ALA4401110	B	Selectivity ratio of IC50 for SHP2 (unknown origin) to IC50 for GST-fused PTP1B catalytic domain (1 to 321 residues) (unknown origin) expressed in Escherichia coli	Homo sapiens	2	ALA4400525	assay format	Scientific Literature
10.	ALA4401111	B	Selectivity ratio of IC50 for LAR (unknown origin) to IC50 for GST-fused PTP1B catalytic domain (1 to 321 residues) (unknown origin) expressed in Escherichia coli	Homo sapiens	2	ALA4400525	assay format	Scientific Literature
11.	ALA4401112	B	Selectivity ratio of IC50 for PTP1B A27S mutant (unknown origin) to IC50 for PTP1B (unknown origin)	Homo sapiens	2	ALA4400525	assay format	Scientific Literature
12.	ALA4401114	B	Competitive inhibition of GST-fused PTP1B catalytic domain (1 to 321 residues) (unknown origin) expressed in Escherichia coli up to 2 uM using varying levels of pNPP as substrate by Lineweaver-Burk double reciprocal plot analysis	Homo sapiens	1	ALA4400525	assay format	Scientific Literature
13.	ALA4401115	B	Binding affinity to human PTP1B (1 to 321 residues) at 50 uM by surface plasmon resonance analysis	Homo sapiens	5	ALA4400525	single protein format	Scientific Literature
14.	ALA4401116	B	Binding affinity to human PTP1B (1 to 321 residues) by surface plasmon resonance analysis	Homo sapiens	1	ALA4400525	single protein format	Scientific Literature
15.	ALA4401117	B	Inhibition of PTP1B in mouse C2C12 cells assessed as suppression of PA-induced insulin resistance by measuring increase in insulin-mediated IRS1 phosphorylation at Y632 residue preincubated for 1 hr followed by palmitic acid stimulation for 16 hrs and subsequent insulin addition measured after 30 mins by Western blot analysis	Mus musculus	1	ALA4400525	cell-based format	Scientific Literature
16.	ALA4401118	B	Inhibition of PTP1B in mouse C2C12 cells assessed as suppression of PA-induced insulin resistance by measuring increase in insulin-mediated AKT phosphorylation at S473 residue preincubated for 1 hr followed by palmitic acid stimulation for 16 hrs and subsequent insulin addition measured after 30 mins by Western blot analysis	Mus musculus	1	ALA4400525	cell-based format	Scientific Literature
17.	ALA4401119	B	Inhibition of PTP1B in PA-stimulated mouse C2C12 cells assessed as increase in JAK2 phosphorylation at Y1007/Y1008 residues preincubated for 1 hr followed by palmitic acid stimulation for 16 hrs and measured by Western blot analysis	Mus musculus	1	ALA4400525	cell-based format	Scientific Literature
18.	ALA4401120	B	Inhibition of PTP1B in PA-stimulated mouse C2C12 cells assessed as increase in STAT3 phosphorylation at Y705 residue preincubated for 1 hr followed by palmitic acid stimulation for 16 hrs and measured by Western blot analysis	Mus musculus	1	ALA4400525	cell-based format	Scientific Literature
19.	ALA4401121	F	Antiobesity activity in BKS db mouse assessed as decrease in food intake at 100 mg/kg, po administered once daily for 5 weeks	Mus musculus	1	ALA4400525	organism-based format	Scientific Literature
20.	ALA4401122	F	Antiobesity activity in BKS db mouse assessed as decrease in water intake at 100 mg/kg, po administered once daily for 5 weeks	Mus musculus	1	ALA4400525	organism-based format	Scientific Literature