#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4414743	Binding	Inhibition of human 5-LO transfected in HEK293 cells coexpressing FLAP assessed as reduction in leukotriene formation at 1 uM using arachidonic acid as substrate preincubated for 5 mins followed by calcium ionophore A23187/arachidonic acid addition and measured after 15 mins by RP-HPLC analysis	Homo sapiens	8	ALA4414547	cell-based format	Scientific Literature
2.	ALA4414744	Binding	Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation at 1 uM preincubated for 5 mins followed by thapsigargin stimulation measured after 15 mins by RP-HPLC analysis relative to control	Homo sapiens	5	ALA4414547	cell-based format	Scientific Literature
3.	ALA4414745	Binding	Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation measured after 15 mins by RP-HPLC analysis	Homo sapiens	5	ALA4414547	cell-based format	Scientific Literature
4.	ALA4414746	Binding	Potency index, ratio of Zileuton IC50 to compound IC50 for inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation measured after 15 mins by RP-HPLC analysis	Homo sapiens	2	ALA4414547	cell-based format	Scientific Literature
5.	ALA4414747	Binding	Potency index, ratio of CAPE IC50 to compound IC50 for inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation measured after 15 mins by RP-HPLC analysis	Homo sapiens	2	ALA4414547	cell-based format	Scientific Literature
6.	ALA4414748	Functional	Antioxidant activity assessed as DPPH radical scavenging activity incubated for 30 mins under dark condition		6	ALA4414547	assay format	Scientific Literature
7.	ALA4414749	Functional	Cytotoxicity against VHL-positive human RCC10 cells assessed as reduction in cell viability incubated for 4 days by XTT assay	Homo sapiens	5	ALA4414547	cell-based format	Scientific Literature
8.	ALA4414751	Functional	Cytotoxicity against VHL-deficient human RCC4 cells assessed as reduction in cell viability incubated for 4 days by XTT assay	Homo sapiens	5	ALA4414547	cell-based format	Scientific Literature
9.	ALA4414752	Functional	Cytotoxicity against VHL-positive human RCC4/VHL cells assessed as reduction in cell viability incubated for 4 days by XTT assay	Homo sapiens	5	ALA4414547	cell-based format	Scientific Literature
10.	ALA4414753	Functional	Cytotoxicity against VHL-deficient human RCC10 cells assessed as reduction in cell viability incubated for 4 days by XTT assay	Homo sapiens	5	ALA4414547	cell-based format	Scientific Literature
11.	ALA4414754	Functional	Cytotoxicity against VHL-deficient human 786-0 cells assessed as reduction in cell viability incubated for 4 days by XTT assay	Homo sapiens	5	ALA4414547	cell-based format	Scientific Literature
12.	ALA4414755	Functional	Cytotoxicity against VHL-positive human 786-0 cells assessed as reduction in cell viability incubated for 4 days by XTT assay	Homo sapiens	5	ALA4414547	cell-based format	Scientific Literature