Assay

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Assay

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#	Aladdin ID	Assay Type	Description	Organism	Compounds	BAO Format	Source
1.	ALA4311836	B	Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by chemifluorescence assay	Homo sapiens	25	single protein format	Scientific Literature
2.	ALA4311837	B	Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by chemifluorescence assay	Homo sapiens	25	assay format	Scientific Literature
3.	ALA4311838	B	Selectivity ratio of IC50 for full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 to IC50 for human PARP10 catalytic domain	Homo sapiens	25	assay format	Scientific Literature