# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4420660 | B | Inhibition of human LATS1 kinase domain (589 to 1130 amino acids) incubated for 30 mins by HTRF assay | Homo sapiens | 244 | single protein format | Patent Bioactivity Data | ||
2. | ALA4420662 | B | Inhibition of human LATS2 kinase domain (553 to 1088 amino acids) incubated for 3 hrs in presence of FAM-KKLRRTLSVA-COOH by fluorescence detection based biochemical caliper assay | Homo sapiens | 244 | single protein format | Patent Bioactivity Data | ||
3. | ALA4420664 | B | Inhibition of LATS in human HaCaT cells assessed as reduction in YAP phosphorylation level incubated for 2 hrs by HTRF assay | Homo sapiens | 244 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4420665 | B | Inhibition of LATS in human HaCaT cells assessed as reduction in YAP nuclear translocation incubated for 24 hrs | Homo sapiens | 244 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4420671 | B | Inhibition of LATS in human JHH5 cells assessed as reduction in YAP phosphorylation level incubated for 2 hrs by HTRF assay | Homo sapiens | 284 | cell-based format | Patent Bioactivity Data |