# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4373082 | B | Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting method | Homo sapiens | 22 | ALA4371070 | single protein format | Scientific Literature | |
2. | ALA4373083 | A | Inhibition of PDE1 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting method | Homo sapiens | 2 | ALA4371070 | protein format | Scientific Literature | |
3. | ALA4373084 | B | Inhibition of PDE4 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting method | Homo sapiens | 2 | ALA4371070 | protein format | Scientific Literature | |
4. | ALA4373085 | B | Inhibition of PDE5 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting method | Homo sapiens | 2 | ALA4371070 | single protein format | Scientific Literature | |
5. | ALA4373086 | B | Inhibition of PDE9 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting method | Homo sapiens | 2 | ALA4371070 | single protein format | Scientific Literature | |
6. | ALA4373087 | B | Inhibition of PDE10 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting method | Homo sapiens | 2 | ALA4371070 | single protein format | Scientific Literature | |
7. | ALA4373088 | B | Selectivity ratio of IC50 for PDE1 (unknown origin) to IC50 for PDE2 (unknown origin) | Homo sapiens | 2 | ALA4371070 | assay format | Scientific Literature | |
8. | ALA4373089 | B | Selectivity ratio of IC50 for PDE4 (unknown origin) to IC50 for PDE2 (unknown origin) | Homo sapiens | 2 | ALA4371070 | assay format | Scientific Literature | |
9. | ALA4373090 | B | Selectivity ratio of IC50 for PDE5 (unknown origin) to IC50 for PDE2 (unknown origin) | Homo sapiens | 2 | ALA4371070 | protein format | Scientific Literature | |
10. | ALA4373091 | B | Selectivity ratio of IC50 for PDE10 (unknown origin) to IC50 for PDE2 (unknown origin) | Homo sapiens | 2 | ALA4371070 | assay format | Scientific Literature | |
11. | ALA4373092 | F | Neuroprotective activity against corticosterone-induced toxicity in mouse HT22 cells assessed as increase in cell viability at 0.01 to 1 uM after 24 hrs by MTS assay | Mus musculus | 2 | ALA4371070 | cell-based format | Scientific Literature |