# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4357184 | Functional | Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4354831 | cell-based format | Scientific Literature | |
2. | ALA4357185 | Functional | Antiproliferative activity against human BE(2)-C cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4354831 | cell-based format | Scientific Literature | |
3. | ALA4357188 | Functional | Antiproliferative activity against human HeLa cells assessed as reduction in cell viability in presence of cisplatin after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4354831 | cell-based format | Scientific Literature | |
4. | ALA4357189 | Functional | Potentiation of cisplatin-induced cytotoxicity against human HeLa cells assessed as cisplatin IC50 after 48 hrs by MTT assay (Rvb = 6.3 +/- 0.8 microM) | Homo sapiens | 5 | ALA4354831 | cell-based format | Scientific Literature | |
5. | ALA4357190 | Functional | Antiproliferative activity against human BE(2)-C cells assessed as reduction in cell viability in presence of cisplatin after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4354831 | cell-based format | Scientific Literature | |
6. | ALA4357191 | Functional | Potentiation of cisplatin-induced cytotoxicity against human BE(2)-C cells assessed as cisplatin IC50 after 48 hrs by MTT assay (Rvb = 5.3 +/- 0.1 microM) | Homo sapiens | 5 | ALA4354831 | cell-based format | Scientific Literature | |
7. | ALA4357192 | Functional | Synergistic antiproliferative activity against human HeLa cells assessed as FICI in presence of cisplatin after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4354831 | cell-based format | Scientific Literature | |
8. | ALA4357193 | Functional | Synergistic antiproliferative activity against human BE(2)-C cells assessed as FICI in presence of cisplatin after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4354831 | cell-based format | Scientific Literature | |
9. | ALA4357195 | Functional | Ratio of IC50 for antiproliferative activity against human HeLa cells to IC50 for antiproliferative activity against human HeLa in presence of cisplatin | Homo sapiens | 2 | ALA4354831 | cell-based format | Scientific Literature | |
10. | ALA4357196 | Functional | Ratio of IC50 for antiproliferative activity against human BE(2)-C cells to IC50 for antiproliferative activity against human BE(2)-C cells in presence of cisplatin | Homo sapiens | 2 | ALA4354831 | cell-based format | Scientific Literature | |
11. | ALA4357201 | Functional | Antiproliferative activity against human HeLa cells assessed as cell viability at 4.7 uM in presence of 6.3 uM cisplatin after 48 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA4354831 | cell-based format | Scientific Literature | |
12. | ALA4357202 | Functional | Antiproliferative activity against human BE(2)-C cells assessed as cell viability at 4.7 uM in presence of 5.3 uM cisplatin after 48 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA4354831 | cell-based format | Scientific Literature | |
13. | ALA4357203 | Functional | Antiproliferative activity against human HeLa cells assessed as cell viability at 4.7 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA4354831 | cell-based format | Scientific Literature | |
14. | ALA4357204 | Functional | Antiproliferative activity against human BE(2)-C cells assessed as cell viability at 4.7 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA4354831 | cell-based format | Scientific Literature | |
15. | ALA4357205 | Binding | Inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate measured every 5 mins for 120 mins by fluorescence based assay | Homo sapiens | 5 | ALA4354831 | protein complex format | Scientific Literature | |
16. | ALA4357206 | Binding | Inhibition of 20S proteasome in human HeLa cells at 2xIC50 using LLVY-R110 peptide as substrate measured up to 36 hrs by fluorescence based assay | Homo sapiens | 2 | ALA4354831 | cell-based format | Scientific Literature | |
17. | ALA4357207 | Binding | Inhibition of 20S proteasome in human BE(2)-C cells at 2xIC50 using LLVY-R110 peptide as substrate measured up to 36 hrs by fluorescence based assay | Homo sapiens | 2 | ALA4354831 | cell-based format | Scientific Literature | |
18. | ALA4357208 | Binding | Potency index, ratio of ixazomib IC50 to compound IC50 for inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate measured every 5 mins for 120 mins by fluorescence based assay | Homo sapiens | 2 | ALA4354831 | protein complex format | Scientific Literature | |
19. | ALA4357209 | Binding | Induction of membrane disruption in human HeLa cells assessed as red fluorescence at 2xIC50 after 24 hrs by SYTO9/PI-staining based inverted fluorescence microscopic analysis | Homo sapiens | 2 | ALA4354831 | cell-based format | Scientific Literature | |
20. | ALA4357210 | Binding | Induction of membrane disruption in human BE(2)-C cells assessed as red fluorescence at 2xIC50 after 24 hrs by SYTO9/PI-staining based inverted fluorescence microscopic analysis | Homo sapiens | 2 | ALA4354831 | cell-based format | Scientific Literature |