# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4351618 | Binding | Binding affinity to human N-terminal His-tagged PCAF by isothermal titration calorimetry | Homo sapiens | 34 | ALA4350961 | single protein format | Scientific Literature | |
2. | ALA4351619 | Binding | Binding affinity to human N-terminal His-tagged PCAF assessed as change in melting temperature at 10 uM by SYPRO orange dye-based fluorescence assay | Homo sapiens | 31 | ALA4350961 | single protein format | Scientific Literature | |
3. | ALA4351666 | Binding | Inhibition of Halo-tagged histone H3.3 binding to N-terminal Nano luciferase-fused full-length PCAF (unknown origin) expressed in HEK293T cells co-expressing C-terminal Halo-tagged histone H3.3 measured after 18 hrs by 618 fluorescent ligand-based BRET assay | Homo sapiens | 2 | ALA4350961 | cell-based format | Scientific Literature | |
4. | ALA4351667 | Functional | Effect on LL6 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
5. | ALA4351668 | Functional | Effect on Unc5a gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
6. | ALA4351669 | Functional | Effect on Slitrk6 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
7. | ALA4351670 | Functional | Effect on Dlx4 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
8. | ALA4351671 | Functional | Effect on Nr4a3 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
9. | ALA4351672 | Functional | Effect on Gm3173 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
10. | ALA4351673 | Functional | Effect on Lonrf3 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
11. | ALA4351674 | Functional | Effect on Gabra4 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
12. | ALA4351675 | Functional | Effect on Clec5a gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
13. | ALA4351676 | Functional | Effect on Slco1a5 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
14. | ALA4351677 | Functional | Effect on Slc26a7 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
15. | ALA4351678 | Functional | Effect on Dmrta2 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
16. | ALA4351679 | Functional | Effect on H60b gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
17. | ALA4351680 | Functional | Effect on Gm36718 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
18. | ALA4351681 | Functional | Effect on Kcnk10 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
19. | ALA4351682 | Functional | Effect on Gabra3 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature | |
20. | ALA4351683 | Functional | Effect on Srcin1 gene expression in MEF cells at 2.5 uM measured after 48 hrs by RNA-sequencing analysis relative to control | Mus musculus | 2 | ALA4350961 | cell-based format | Scientific Literature |