#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4403717	Binding	Binding affinity to GABA-A alpha2 (unknown origin)	Homo sapiens	26	ALA4402545	single protein format	Scientific Literature
2.	ALA4403718	Binding	Binding affinity to GABA-A alpha1 (unknown origin)	Homo sapiens	18	ALA4402545	single protein format	Scientific Literature
3.	ALA4403719	Binding	Binding affinity to GABA-A alpha3 (unknown origin)	Homo sapiens	18	ALA4402545	single protein format	Scientific Literature
4.	ALA4403720	Binding	Binding affinity to GABA-A alpha5 (unknown origin)	Homo sapiens	16	ALA4402545	single protein format	Scientific Literature
5.	ALA4403774	Binding	Negative allosteric modulation of GABA-A alpha1 (unknown origin) assessed as reduction in DMCM induced current relative to control	Homo sapiens	5	ALA4402545	single protein format	Scientific Literature
6.	ALA4403775	Binding	Binding affinity to GABA-A alpha2 (unknown origin) assessed as reduction in DMCM induced current relative to control	Homo sapiens	5	ALA4402545	single protein format	Scientific Literature
7.	ALA4403776	Binding	Binding affinity to GABA-A alpha3 (unknown origin) assessed as reduction in DMCM induced current relative to control	Homo sapiens	5	ALA4402545	single protein format	Scientific Literature
8.	ALA4403777	Binding	Binding affinity to GABA-A alpha5 (unknown origin) assessed as reduction in DMCM induced current relative to control	Homo sapiens	5	ALA4402545	single protein format	Scientific Literature
9.	ALA4403790	Functional	In vivo receptor occupancy at GABAA receptor in po dosed Crl:CD Sprague-Dawley rat assessed as brain concentration causing 50% reduction in [3H]-Ro15-4513 receptor labeling after 1 hr	Rattus norvegicus	1	ALA4402545	organism-based format	Scientific Literature
10.	ALA4701822	Binding	Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assay	Homo sapiens	35	ALA4699487	protein complex format	Scientific Literature
11.	ALA4701823	Binding	Negative allosteric modulation of recombinant human GABA-A alpha5 expressed in HEK293 cells assessed as reduction in GABA-induced current at 1 uM relative to control	Homo sapiens	30	ALA4699487	cell-based format	Scientific Literature
12.	ALA4701824	ADME	Negative allosteric modulation of recombinant human GABA-A alpha1 expressed in HEK293 cells assessed as reduction in GABA-induced current at 1 uM relative to control	Homo sapiens	22	ALA4699487	cell-based format	Scientific Literature
13.	ALA4701826	ADME	Negative allosteric modulation of recombinant human GABA-A alpha3 expressed in HEK293 cells assessed as reduction in GABA-induced current at 1 uM relative to control	Homo sapiens	21	ALA4699487	cell-based format	Scientific Literature
14.	ALA4701827	ADME	Half life in rat liver microsomes	Rattus norvegicus	31	ALA4699487	microsome format	Scientific Literature
15.	ALA4701828	ADME	Half life in human liver microsomes	Homo sapiens	31	ALA4699487	microsome format	Scientific Literature
16.	ALA4701829	ADME	Apparent permeability in MDCK-MDR1 cells	Canis lupus familiaris	1	ALA4699487	cell-based format	Scientific Literature
17.	ALA4701830	ADME	Efflux ratio of apparent permeability in MDCK-MDR1 cells	Canis lupus familiaris	1	ALA4699487	cell-based format	Scientific Literature
18.	ALA4701831	ADME	Protein binding in rat plasma	Rattus norvegicus	1	ALA4699487	cell-free format	Scientific Literature
19.	ALA4701832	ADME	Protein binding in rat brain homogenate	Rattus norvegicus	1	ALA4699487	tissue-based format	Scientific Literature
20.	ALA4701833	Functional	In vivo receptor occupancy at GABAA alpha5 receptor in rat brain assessed as reduction in [3H]-Ro15-4513 receptor labeling at 10 mg/kg, po measured after 1 hr relative to control	Rattus norvegicus	1	ALA4699487	organism-based format	Scientific Literature