# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4341005 | Functional | Vasodilating activity in Sprague-Dawley rat aortic rings assessed as reduction in phenylephrine-induced contractions | Rattus norvegicus | 12 | ALA4340513 | tissue-based format | Scientific Literature | |
2. | ALA4341006 | Functional | Vasodilating activity in Sprague-Dawley rat aortic rings assessed as reduction in phenylephrine-induced contractions relative to control | Rattus norvegicus | 12 | ALA4340513 | tissue-based format | Scientific Literature | |
3. | ALA4341008 | Functional | Vasodilating activity in Sprague-Dawley rat aortic rings assessed as reduction in phenylephrine-induced contractions in presence of L-cysteine and TRPV1 antagonist capsazepine | Rattus norvegicus | 1 | ALA4340513 | tissue-based format | Scientific Literature | |
4. | ALA4341009 | Functional | Vasodilating activity in Sprague-Dawley rat aortic rings assessed as reduction in phenylephrine-induced contractions in presence of L-cysteine and TRPA1 antagonist HC030031 | Rattus norvegicus | 1 | ALA4340513 | tissue-based format | Scientific Literature | |
5. | ALA4341010 | Functional | Vasodilating activity in Sprague-Dawley rat aortic rings assessed as reduction in phenylephrine-induced contractions in presence of L-cysteine and CGRP receptor antagonist CGRP(8 to 37) | Rattus norvegicus | 1 | ALA4340513 | tissue-based format | Scientific Literature | |
6. | ALA4341011 | Functional | Antihypertensive activity in carotid cannulated Sprague-Dawley rat assessed as reduction in systolic arterial pressure at 20 to 40 mg/kg, ip measured within 2 hrs relative to rutaecarpine | Rattus norvegicus | 1 | ALA4340513 | organism-based format | Scientific Literature | |
7. | ALA4341012 | Functional | Antihypertensive activity in carotid cannulated Sprague-Dawley rat assessed as reduction in diastolic arterial pressure at 20 to 40 mg/kg, ip measured within 2 hrs relative to rutaecarpine | Rattus norvegicus | 1 | ALA4340513 | organism-based format | Scientific Literature | |
8. | ALA4341013 | Functional | Increase in CGRP level in Sprague-Dawley rat blood at 20 to 40 mg/kg, ip by ELISA | Rattus norvegicus | 2 | ALA4340513 | organism-based format | Scientific Literature |