# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4348124 | Functional | Induction of apoptosis in human MCF7/PTX cells assessed as late apoptotic cells at 3 uM incubated for 12 hrs by Annexin V-FITC/propidium iodide staining based flow cytometric analysis (Rvb = 0.9%) | Homo sapiens | 7 | ALA4346678 | cell-based format | Scientific Literature | |
2. | ALA4348126 | Functional | Cytotoxicity against human MCF7 cells incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4346678 | cell-based format | Scientific Literature | |
3. | ALA4348127 | Functional | Cytotoxicity against human MCF7/PTX cells incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4346678 | cell-based format | Scientific Literature | |
4. | ALA4348128 | Functional | Cytotoxicity against human K562 cells incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4346678 | cell-based format | Scientific Literature | |
5. | ALA4348129 | Functional | Cytotoxicity against human A2780 cells incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4346678 | cell-based format | Scientific Literature | |
6. | ALA4348130 | Functional | Cytotoxicity against human SKOV3 cells incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4346678 | cell-based format | Scientific Literature | |
7. | ALA4348132 | ADME | Cytotoxicity against HUVEC incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4346678 | cell-based format | Scientific Literature | |
8. | ALA4348136 | Functional | Induction of apoptosis in human MCF7/PTX cells assessed as necrotic cells at 3 uM incubated for 12 hrs by Annexin V-FITC/propidium iodide staining based flow cytometric analysis (Rvb = 2.1%) | Homo sapiens | 7 | ALA4346678 | cell-based format | Scientific Literature | |
9. | ALA4348137 | Functional | Induction of apoptosis in human MCF7/PTX cells assessed as live cells at 3 uM incubated for 12 hrs by Annexin V-FITC/propidium iodide staining based flow cytometric analysis (Rvb = 95.9%) | Homo sapiens | 7 | ALA4346678 | cell-based format | Scientific Literature | |
10. | ALA4348138 | Functional | Induction of apoptosis in human MCF7/PTX cells assessed as early apoptotic cells at 3 uM incubated for 12 hrs by Annexin V-FITC/propidium iodide staining based flow cytometric analysis (Rvb = 1.1%) | Homo sapiens | 7 | ALA4346678 | cell-based format | Scientific Literature | |
11. | ALA4348154 | ADME | Half life in Wistar rat plasma at 500 ug/ml measured over 24 hrs at 37 degC by UPLC/MS analysis | Rattus norvegicus | 2 | ALA4346678 | cell-free format | Scientific Literature | |
12. | ALA4348157 | Functional | Induction of apoptosis in human MCF7/PTX cells assessed as live cells at 3 uM incubated for 12 hrs by Annexin V-FITC/propidium iodide staining based flow cytometric analysis in presence of paclitaxel (Rvb = 95.9%) | Homo sapiens | 1 | ALA4346678 | cell-based format | Scientific Literature | |
13. | ALA4348158 | Functional | Induction of apoptosis in human MCF7/PTX cells assessed as early apoptotic cells at 3 uM incubated for 12 hrs by Annexin V-FITC/propidium iodide staining based flow cytometric analysis in presence of paclitaxel (Rvb = 1.1%) | Homo sapiens | 1 | ALA4346678 | cell-based format | Scientific Literature | |
14. | ALA4348159 | Functional | Induction of apoptosis in human MCF7/PTX cells assessed as late apoptotic cells at 3 uM incubated for 12 hrs by Annexin V-FITC/propidium iodide staining based flow cytometric analysis in presence of paclitaxel (Rvb = 0.9%) | Homo sapiens | 1 | ALA4346678 | cell-based format | Scientific Literature | |
15. | ALA4348160 | Functional | Induction of apoptosis in human MCF7/PTX cells assessed as necrotic cells at 3 uM incubated for 12 hrs by Annexin V-FITC/propidium iodide staining based flow cytometric analysis in presence of paclitaxel (Rvb = 2.1%) | Homo sapiens | 1 | ALA4346678 | cell-based format | Scientific Literature |