# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4417982 | Functional | Inhibition of IL12-stimulated IFNgamma production in PHA-activated human PBMC at 0.0001 to 100 uM by ELISA | Homo sapiens | 2 | ALA4417631 | cell-based format | Patent Bioactivity Data | |
2. | ALA4417984 | Functional | Anti-colitis activity in Sprague-Dawley rat model of DSS-induced colitis assessed as change in body weight at 30 mg/kg, po dosed 3 times per day (-6.39 +/- 1.11%) | Rattus norvegicus | 1 | ALA4417631 | organism-based format | Patent Bioactivity Data | |
3. | ALA4417987 | Functional | Anti-colitis activity in Sprague-Dawley rat model of DSS-induced colitis assessed as reduction in disease activity index at 30 mg/kg, po dosed 3 times per day | Rattus norvegicus | 1 | ALA4417631 | organism-based format | Patent Bioactivity Data | |
4. | ALA4417990 | Functional | Anti-colitis activity in Sprague-Dawley rat model of DSS-induced colitis assessed as colon weight/colon length ratio at 30 mg/kg, po dosed 3 times per day (124.36 +/- 17.11 g/cm) | Rattus norvegicus | 1 | ALA4417631 | organism-based format | Patent Bioactivity Data | |
5. | ALA4417993 | Functional | Anti-colitis activity in Sprague-Dawley rat model of DSS-induced colitis assessed as reduction in colon macroscopic scores at 30 mg/kg, ip dosed 3 times per day | Rattus norvegicus | 1 | ALA4417631 | organism-based format | Patent Bioactivity Data | |
6. | ALA4417994 | Functional | Anti-colitis activity in Sprague-Dawley rat model of DSS-induced colitis assessed as reduction in colon macroscopic scores at 30 mg/kg, po dosed 3 times per day | Rattus norvegicus | 1 | ALA4417631 | organism-based format | Patent Bioactivity Data | |
7. | ALA4417997 | Functional | Anti-colitis activity in Sprague-Dawley rat model of DSS-induced colitis assessed as improvement in stool consistency scores level at 30 mg/kg, ip dosed 3 times per day | Rattus norvegicus | 1 | ALA4417631 | organism-based format | Patent Bioactivity Data | |
8. | ALA4417998 | Functional | Anti-colitis activity in Sprague-Dawley rat model of DSS-induced colitis assessed as improvement in hematocrit scores level at 30 mg/kg, ip dosed 3 times per day | Rattus norvegicus | 1 | ALA4417631 | organism-based format | Patent Bioactivity Data | |
9. | ALA4417999 | Functional | Anti-colitis activity in Sprague-Dawley rat model of DSS-induced colitis assessed as improvement in stool consistency scores level at 30 mg/kg, po dosed 3 times per day | Rattus norvegicus | 1 | ALA4417631 | organism-based format | Patent Bioactivity Data | |
10. | ALA4418000 | Functional | Anti-colitis activity in Sprague-Dawley rat model of DSS-induced colitis assessed as improvement in hematocrit scores level at 30 mg/kg, po dosed 3 times per day | Rattus norvegicus | 1 | ALA4417631 | organism-based format | Patent Bioactivity Data |