| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4397793 | B | Displacement of [3H]-NMS from human muscarinic M1 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting method | Homo sapiens | 31 | ALA4396879 | cell-based format | Scientific Literature | |
| 2. | ALA4397794 | B | Displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting method | Homo sapiens | 31 | ALA4396879 | cell-based format | Scientific Literature | |
| 3. | ALA4397795 | B | Displacement of [3H]-NMS from human muscarinic M3 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting method | Homo sapiens | 31 | ALA4396879 | cell-based format | Scientific Literature | |
| 4. | ALA4397796 | B | Displacement of [3H]-NMS from human muscarinic M4 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting method | Homo sapiens | 31 | ALA4396879 | cell-based format | Scientific Literature | |
| 5. | ALA4397797 | B | Displacement of [3H]-NMS from human muscarinic M5 receptor expressed in CHO-K9 cells after 3 hrs by microbeta2 scintillation counting method | Homo sapiens | 31 | ALA4396879 | cell-based format | Scientific Literature | |
| 6. | ALA4397798 | B | Selectivity ratio of Ki for human muscarinic M1 receptor expressed in CHO-K9 cells to Ki for human muscarinic M2 receptor expressed in CHO-K9 cells | Homo sapiens | 31 | ALA4396879 | cell-based format | Scientific Literature | |
| 7. | ALA4397799 | B | Selectivity ratio of Ki for human muscarinic M3 receptor expressed in CHO-K9 cells to Ki for human muscarinic M2 receptor expressed in CHO-K9 cells | Homo sapiens | 31 | ALA4396879 | cell-based format | Scientific Literature | |
| 8. | ALA4397800 | B | Selectivity ratio of Ki for human muscarinic M4 receptor expressed in CHO-K9 cells to Ki for human muscarinic M2 receptor expressed in CHO-K9 cells | Homo sapiens | 31 | ALA4396879 | cell-based format | Scientific Literature | |
| 9. | ALA4397801 | B | Selectivity ratio of Ki for human muscarinic M5 receptor expressed in CHO-K9 cells to Ki for human muscarinic M2 receptor expressed in CHO-K9 cells | Homo sapiens | 31 | ALA4396879 | cell-based format | Scientific Literature | |
| 10. | ALA4397802 | F | Agonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as induction of Galphaq/i5-mediated IP1 accumulation after 1 hr by HTRF assay | Homo sapiens | 3 | ALA4396879 | cell-based format | Scientific Literature | |
| 11. | ALA4397803 | F | Antagonist activity at human muscarinic M2 receptor expressed in HEK293 cells co-expressing HA-Galphaq/i5 assessed as inhibition of carbachol-induced IP1 accumulation pre-incubated for 30 mins followed by carbachol addition and measured after 1 hr by HTRF assay | Homo sapiens | 3 | ALA4396879 | cell-based format | Scientific Literature | |
| 12. | ALA4397804 | A | Stability of the compound in human plasma:PBS of pH 7.4 (1:2) assessed as intact compound at 100 uM incubated for 1 hr by LC-MS analysis | Homo sapiens | 3 | ALA4396879 | cell-free format | Scientific Literature | |
| 13. | ALA4397805 | A | Stability of the compound in human plasma used as 1:2 ratio of plasma to pH 7.4 PBS assessed as intact compound at 100 uM incubated for 6 hr by LC-MS analysis | Homo sapiens | 3 | ALA4396879 | cell-free format | Scientific Literature | |
| 14. | ALA4397806 | A | Stability of the compound in human plasma used as 1:2 ratio of plasma to pH 7.4 PBS assessed as intact compound at 100 uM incubated for 24 hr by LC-MS analysis | Homo sapiens | 3 | ALA4396879 | cell-free format | Scientific Literature | |
| 15. | ALA4397807 | A | Stability of the compound in human plasma used as 1:2 ratio of plasma to pH 7.4 PBS assessed as intact compound at 100 uM incubated for 48 hr by LC-MS analysis | Homo sapiens | 3 | ALA4396879 | cell-free format | Scientific Literature | |
| 16. | ALA4397808 | B | Competitive displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO-K9 cells using 0.2 nM [3H]-NMS after 3 hrs by microbeta2 scintillation counting method | Homo sapiens | 2 | ALA4396879 | cell-based format | Scientific Literature | |
| 17. | ALA4397809 | B | Competitive displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO-K9 cells using 2 nM [3H]-NMS after 3 hrs by microbeta2 scintillation counting method | Homo sapiens | 2 | ALA4396879 | cell-based format | Scientific Literature | |
| 18. | ALA4397810 | B | Competitive displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO-K9 cells using 2 nM [3H]-NMS after 3 hrs by microbeta2 scintillation counting method relative to control | Homo sapiens | 2 | ALA4396879 | cell-based format | Scientific Literature |
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