# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4354023 | Functional | Antagonist activity at human 5HT6 receptor expressed in HEK293 cells assessed as inhibition of 5-CT induced cAMP production measured after 30 mins by TR-FRET assay | Homo sapiens | 6 | ALA4351001 | cell-based format | Scientific Literature | |
2. | ALA4354024 | Binding | Displacement of [3H] prazosin from rat alpha 1A adrenergic receptor at 10'-6 M measured after 60 mins by scintillation counter method relative to control | Rattus norvegicus | 6 | ALA4351001 | single protein format | Scientific Literature | |
3. | ALA4354025 | Binding | Displacement of [3H] pyrilamine from human recombinant H1 histamine receptor at 10'-6 M measured after 60 mins by scintillation counting method relative to control | Homo sapiens | 6 | ALA4351001 | single protein format | Scientific Literature | |
4. | ALA4354026 | Binding | Agonist activity at human recombinant H1 histamine receptor at 10'-5 M relative to control | Homo sapiens | 6 | ALA4351001 | single protein format | Scientific Literature | |
5. | ALA4354027 | Binding | Antagonist activity at human recombinant H1 histamine receptor at 10'-5 M relative to control | Homo sapiens | 6 | ALA4351001 | single protein format | Scientific Literature | |
6. | ALA4354028 | Binding | Displacement of [3H] pirenzepine from human recombinant muscarinic M1 receptor at 10'-6 M measured after 60 mins by scintillation counter method relative to control | Homo sapiens | 6 | ALA4351001 | single protein format | Scientific Literature | |
7. | ALA4354029 | Binding | Displacement of [3H]4-DAMP from human recombinant muscarinic M5 receptor at 10'-6 M measured after 60 mins by scintillation counter method relative to control | Homo sapiens | 6 | ALA4351001 | single protein format | Scientific Literature | |
8. | ALA4354030 | Binding | Displacement of [3H]mesulergine from human recombinant 5HT2C serotonin receptor at 10'-6M incubated for 120 mins by scintillation counter method relative to control | Homo sapiens | 6 | ALA4351001 | single protein format | Scientific Literature | |
9. | ALA4354031 | Binding | Agonist activity at human 5HT2C serotonin receptor at 10'-5 M relative to control | Homo sapiens | 6 | ALA4351001 | single protein format | Scientific Literature | |
10. | ALA4354032 | Binding | Antagonist activity at human 5HT2C serotonin receptor at 10'-5 M relative to control | Homo sapiens | 6 | ALA4351001 | single protein format | Scientific Literature | |
11. | ALA4354033 | Binding | Displacement of [3H] dofetilide from human recombinant ERG at 10'-6 M measured after 60 mins by scintillation counting method relative to control | Homo sapiens | 6 | ALA4351001 | single protein format | Scientific Literature | |
12. | ALA4354034 | Binding | Antagonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells at 10'-6 M measured after 30 mins by HTRF assay relative to control | Homo sapiens | 6 | ALA4351001 | cell-based format | Scientific Literature | |
13. | ALA4354035 | Binding | Displacement of [3H] mesulergine from human recombinant 5HT2B receptor at 10'-6 M measured after 60 mins by scintillation counting method relative to control | Homo sapiens | 6 | ALA4351001 | single protein format | Scientific Literature | |
14. | ALA4354036 | Physicochemical | Solubility of compound in water | 53 | ALA4351001 | small-molecule physicochemical format | Scientific Literature |