| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4327018 | B | Inhibition of recombinant human endothelial lipase expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followed by substrate addition and measured after 30 mins by LC/MS/MS analysis | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 2. | ALA4327019 | B | Inhibition of endothelial lipase (unknown origin) using D31-POPC-HDL as substrate after 2 hrs in presence of human serum by LC/MS analysis | Homo sapiens | 15 | single protein format | Scientific Literature | ||
| 3. | ALA4327020 | A | Metabolic stability in mouse liver microsomes assessed as parent compound remaining after 10 mins | Mus musculus | 8 | microsome format | Scientific Literature | ||
| 4. | ALA4327021 | A | Permeability of compound at pH 5.5 by PAMPA | 8 | assay format | Scientific Literature | |||
| 5. | ALA4327022 | A | Permeability of compound at pH 7.4 by PAMPA | 8 | assay format | Scientific Literature | |||
| 6. | ALA4327023 | A | Unbound plasma concentration in mouse at 1 mg/kg, iv | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 7. | ALA4327024 | A | AUC in mouse at 1 mg/kg, iv | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 8. | ALA4327025 | A | AUC in mouse at 1 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4327026 | A | Half life in mouse at 1 mg/kg, iv | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 10. | ALA4327027 | A | Bioavailability in mouse at 1 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4327028 | A | Oral bioavailability in mouse at 1 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature |
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