| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4480048 | Functional | Antiproliferative activity against human K562/ADR cells after 72 hrs by CCK8 assay | Homo sapiens | 13 | ALA4477261 | cell-based format | Scientific Literature | |
| 2. | ALA4480049 | Functional | Antiproliferative activity against human K562 cells after 72 hrs by CCK8 assay | Homo sapiens | 13 | ALA4477261 | cell-based format | Scientific Literature | |
| 3. | ALA4480050 | Functional | Resistance factor, ratio of IC50 for human K562/ADR cells to IC50 for human K562 cells | Homo sapiens | 13 | ALA4477261 | cell-based format | Scientific Literature | |
| 4. | ALA4480051 | Functional | Potency index, ratio of podophyllotoxin IC50 to compound IC50 for human K562/ADR cells | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature | |
| 5. | ALA4480052 | Functional | Potency index, ratio of etoposide IC50 to compound IC50 for human K562/ADR cells | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature | |
| 6. | ALA4480053 | Functional | Potency index, ratio of adriamycin IC50 to compound IC50 for human K562/ADR cells | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature | |
| 7. | ALA4480054 | Functional | Potency index, ratio of etoposide IC50 to compound IC50 for human K562 cells | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature | |
| 8. | ALA4480055 | Functional | Potency index, ratio of adriamycin IC50 to compound IC50 for human K562 cells | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature | |
| 9. | ALA4480056 | Functional | Cell cycle arrest in human K562/ADR cells assessed as accumulation in S phase at 0.05 uM after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 43.39 +/- 0.69%) | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature | |
| 10. | ALA4480057 | Functional | Cell cycle arrest in human K562/ADR cells assessed as accumulation in S phase at 0.1 uM after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 43.39 +/- 0.69%) | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature | |
| 11. | ALA4480059 | Functional | Induction of apoptosis in human K562/ADR cells assessed as live cells at 0.05 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 91.65%) | Homo sapiens | 2 | ALA4477261 | cell-based format | Scientific Literature | |
| 12. | ALA4480060 | Functional | Induction of apoptosis in human K562/ADR cells assessed as early apoptotic cells at 0.05 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 1.99%) | Homo sapiens | 2 | ALA4477261 | cell-based format | Scientific Literature | |
| 13. | ALA4480061 | Functional | Induction of apoptosis in human K562/ADR cells assessed as late apoptotic cells at 0.05 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 3.89%) | Homo sapiens | 2 | ALA4477261 | cell-based format | Scientific Literature | |
| 14. | ALA4480062 | Functional | Induction of apoptosis in human K562/ADR cells assessed as necrotic cells at 0.05 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 2.47%) | Homo sapiens | 2 | ALA4477261 | cell-based format | Scientific Literature | |
| 15. | ALA4480063 | Functional | Induction of apoptosis in human K562/ADR cells assessed as live cells at 0.1 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 91.65%) | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature | |
| 16. | ALA4480064 | Functional | Induction of apoptosis in human K562/ADR cells assessed as early apoptotic cells at 0.1 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 1.99%) | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature | |
| 17. | ALA4480065 | Functional | Induction of apoptosis in human K562/ADR cells assessed as late apoptotic cells at 0.1 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 3.89%) | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature | |
| 18. | ALA4480066 | Functional | Induction of apoptosis in human K562/ADR cells assessed as necrotic cells at 0.1 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 2.47%) | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature | |
| 19. | ALA4480067 | Functional | Induction of apoptosis in human K562/ADR cells assessed as nuclear fragmentation at 0.05 to 0.1 uM after 48 hrs by Hoechst 33342 staining based fluorescent microscopic analysis | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature | |
| 20. | ALA4480069 | Functional | Induction of apoptosis in human K562/ADR cells assessed as chromatin condensation at 0.05 to 0.1 uM after 48 hrs by Hoechst 33342 staining based fluorescent microscopic analysis | Homo sapiens | 1 | ALA4477261 | cell-based format | Scientific Literature |
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