# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4339621 | B | Negative allosteric modulation of recombinant rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current response at 10 uM at -40 mV holding potential by two-electrode voltage clamp method relative to glutamate/glycine | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
2. | ALA4339622 | B | Negative allosteric modulation of recombinant rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current response at -40 mV holding potential by two-electrode voltage clamp method | Rattus norvegicus | 15 | cell-based format | Scientific Literature | ||
3. | ALA4339623 | B | Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current response at 10 uM at -40 mV holding potential by two-electrode voltage clamp method relative to glutamate/glycine | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
4. | ALA4339624 | B | Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current response at -40 mV holding potential by two-electrode voltage clamp method | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
5. | ALA4339636 | B | Negative allosteric modulation of recombinant rat GluA1 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current response at 30 uM at -40 mV holding potential by two-electrode voltage clamp method relative to glutamate alone | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
6. | ALA4339637 | B | Negative allosteric modulation of human GluA2 R607Q mutant expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current response at 30 uM at -40 mV holding potential by two-electrode voltage clamp method relative to glutamate alone | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA4339638 | B | Negative allosteric modulation of human GluA3 L513Y mutant expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current response at 30 uM at -40 mV holding potential by two-electrode voltage clamp method relative to glutamate alone | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA4339639 | B | Negative allosteric modulation of human GluA4 L505Y mutant expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current response at 30 uM at -40 mV holding potential by two-electrode voltage clamp method relative to glutamate alone | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA4339640 | B | Negative allosteric modulation of rat GluK2 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current response at 30 uM at -40 mV holding potential in presence of concanavalin A by two-electrode voltage clamp method relative to glutamate alone | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
10. | ALA4339642 | B | Negative allosteric modulation of rat GABAA alpha1beta2gamma2S expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current response at 30 uM at -40 mV holding potential by two-electrode voltage clamp method relative to GABA alone | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
11. | ALA4339643 | B | Negative allosteric modulation of rat GABAA rho expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current response at 30 uM at -40 mV holding potential by two-electrode voltage clamp method relative to GABA alone | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
12. | ALA4339644 | B | Negative allosteric modulation of rat glycine alpha1 expressed in Xenopus laevis oocytes assessed as inhibition of glycine-induced current response at 30 uM at -40 mV holding potential by two-electrode voltage clamp method relative to glycine alone | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
13. | ALA4339645 | B | Negative allosteric modulation of rat 5HT3A expressed in Xenopus laevis oocytes assessed as inhibition of serotonin-induced current response at 30 uM at -40 mV holding potential by two-electrode voltage clamp method relative to serotonin alone | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
14. | ALA4339646 | B | Negative allosteric modulation of rat alpha1betagammadelta nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response at 30 uM at -40 mV holding potential by two-electrode voltage clamp method relative to acetylcholine alone | Rattus norvegicus | 2 | cell-based format | Scientific Literature |