# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4391164 | Binding | Inhibition of human recombinant AChE using ATCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellman method | Homo sapiens | 9 | ALA4390652 | single protein format | Scientific Literature | |
2. | ALA4391165 | Binding | Inhibition of human serum BChE using BTCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellman's method | Homo sapiens | 9 | ALA4390652 | single protein format | Scientific Literature | |
3. | ALA4391166 | Binding | Selectivity index, ratio of IC50 for human serum BChE to IC50 for human recombinant AChE | Homo sapiens | 9 | ALA4390652 | protein format | Scientific Literature | |
4. | ALA4391167 | Binding | Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillation counting assay | Sus scrofa | 24 | ALA4390652 | assay format | Scientific Literature | |
5. | ALA4391168 | Binding | Inhibition of human recombinant CDK5/p25 using histone H1 as substrate in presence of [gamma-33P]ATP incubated for 30 mins by liquid scintillation counting assay | Homo sapiens | 24 | ALA4390652 | protein complex format | Scientific Literature | |
6. | ALA4391169 | ADME | Cytotoxicity against human HuH7 cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
7. | ALA4391170 | ADME | Cytotoxicity against human Caco2 cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
8. | ALA4391171 | ADME | Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
9. | ALA4391172 | ADME | Cytotoxicity against human HCT116 cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
10. | ALA4391173 | ADME | Cytotoxicity against human PC3 cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
11. | ALA4391174 | ADME | Cytotoxicity against human NCI-H727 cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature | |
12. | ALA4391175 | ADME | Cytotoxicity against human HaCaT cells assessed as growth inhibition incubated for 48 hrs by Hoechst 33342 staining based assay | Homo sapiens | 8 | ALA4390652 | cell-based format | Scientific Literature |