# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4338378 | Binding | Inhibition of human Cathepsin L assessed as first-order rate constant using Cbz-Phe-Arg-AMC as substrate by fluorescence assay | Homo sapiens | 15 | ALA4334522 | single protein format | Scientific Literature | |
2. | ALA4338379 | Binding | Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris at 50 uM measured for 30 mins using Cbz-Phe-Arg-AMC as substrate by fluorescence assay relative to control | Trypanosoma brucei rhodesiense | 15 | ALA4334522 | assay format | Scientific Literature | |
3. | ALA4338381 | Binding | Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris assessed as first-order rate constant measured for 30 mins using Cbz-Phe-Arg-AMC as substrate by fluorescence assay | Trypanosoma brucei rhodesiense | 15 | ALA4334522 | assay format | Scientific Literature | |
4. | ALA4338382 | Binding | Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris assessed as inhibition constant measured for 30 mins using Cbz-Phe-Arg-AMC as substrate by fluorescence assay | Trypanosoma brucei rhodesiense | 15 | ALA4334522 | assay format | Scientific Literature | |
5. | ALA4338383 | Binding | Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris assessed as second order rate constant obtained from ratio of Kinact to Ki measured for 30 mins using Cbz-Phe-Arg-AMC as substrate by fluorescence assay | Trypanosoma brucei rhodesiense | 15 | ALA4334522 | assay format | Scientific Literature | |
6. | ALA4338384 | Binding | Inhibition of human Cathepsin L assessed as inhibition constant using Cbz-Phe-Arg-AMC as substrate by fluorescence assay | Homo sapiens | 15 | ALA4334522 | single protein format | Scientific Literature | |
7. | ALA4338385 | Binding | Inhibition of human Cathepsin L assessed as second order rate constant obtained from ratio of Kinact to Ki using Cbz-Phe-Arg-AMC as substrate by fluorescence assay | Homo sapiens | 15 | ALA4334522 | single protein format | Scientific Literature | |
8. | ALA4338386 | Functional | Antitrypanosomal activity against blood stage form of Trypanosoma brucei brucei 449 incubated for 24 hrs by ATPlite assay | Trypanosoma brucei brucei | 6 | ALA4334522 | organism-based format | Scientific Literature | |
9. | ALA4338387 | Functional | Antitrypanosomal activity against blood stage form of Trypanosoma brucei brucei 449 incubated for 48 hrs by ATPlite assay | Trypanosoma brucei brucei | 6 | ALA4334522 | organism-based format | Scientific Literature |