| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4395090 | B | Inhibition of recombinant His-tagged human PDE4B expressed in Sf9 cells using cAMP as substrate preincubated with enzyme for 15 mins followed by substrate addition and incubated for 1 hr by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA4395091 | B | Inhibition of human recombinant His-tagged PDE4B expressed in Sf9 cells using cAMP as substrate at 10 uM preincubated with enzyme for 15 mins followed by substrate addition and incubated for 1 hr by PDELight HTS cAMP phosphodiesterase Kit based luminometry relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 3. | ALA4395092 | A | Inhibition of PDE4D2 (unknown origin) using cAMP as substrate preincubated with enzyme for 15 mins followed by substrate addition and incubated for 1 hr by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 4. | ALA4395093 | U | Selectivity index, ratio of IC50 for PDE4D2 (unknown origin) to IC50 for recombinant His-tagged human PDE4B expressed in sf9 cells using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit based luminometry | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA4395094 | A | Inhibition of PDE4C (unknown origin) at 100 uM using cAMP as substrate preincubated with enzyme for 15 mins followed by substrate addition and incubated for 1 hr by PDELight HTS cAMP phosphodiesterase Kit based luminometry relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 6. | ALA4395096 | B | Selectivity for recombinant His-tagged human PDE4B over PDE4C (unknown origin) | Homo sapiens | 2 | assay format | Scientific Literature |
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