# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4346333 | B | Inhibition of human N-terminal His6 tagged BRD4 BD1 (57 to 168) residues expressed in Escherichia coli BL21(DE3) cells after 1 hr by TR-FRET assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
2. | ALA4346334 | B | Inhibition of human N-terminal His6 tagged BRD4 BD2 (352 to 457) residues expressed in Escherichia coli BL21(DE3) cells after 1 hr by TR-FRET assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
3. | ALA4346335 | B | Selectivity index, ratio of Ki for human N-terminal His6 tagged BRD4 BD1 (57 to 168) residues expressed in Escherichia coli BL21(DE3) cells to Ki for inhibition of human N-terminal His6 tagged BRD4 BD2 (352 to 457) residues expressed in Escherichia coli BL21(DE3) cells | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
4. | ALA4346336 | F | Antiproliferative activity against human SKM1 cells assessed as reduction in cell viability after 5 days by CellTiter-Glo assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
5. | ALA4346337 | F | Antiproliferative activity against human H1299 cells assessed as reduction in cell viability after 5 days by CellTiter-Glo assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
6. | ALA4346338 | A | Unbound hepatic clearance in human liver microsomes | Homo sapiens | 45 | microsome format | Scientific Literature | ||
7. | ALA4346339 | A | Unbound hepatic clearance in mouse liver microsomes | Mus musculus | 41 | microsome format | Scientific Literature | ||
8. | ALA4346340 | A | Unbound hepatic clearance in rat liver microsomes | Rattus norvegicus | 41 | microsome format | Scientific Literature | ||
9. | ALA4346341 | A | Permeability in dog MDCK cells by PAMPA | Canis lupus familiaris | 45 | cell-based format | Scientific Literature |