| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4331380 | F | Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay | Homo sapiens | 20 | ALA4330077 | cell-based format | Scientific Literature | |
| 2. | ALA4331381 | B | Inhibition of sheep brain tubulin polymerization by DAPI-fluorescence based fluorimetry | Ovis aries | 20 | ALA4330077 | assay format | Scientific Literature | |
| 3. | ALA4331382 | F | Antiproliferative activity against human A549 cells after 72 hrs by MTS assay | Homo sapiens | 5 | ALA4330077 | cell-based format | Scientific Literature | |
| 4. | ALA4331383 | F | Antiproliferative activity against human U87MG cells after 72 hrs by MTS assay | Homo sapiens | 5 | ALA4330077 | cell-based format | Scientific Literature | |
| 5. | ALA4331384 | F | Antiproliferative activity against human K562 cells after 72 hrs by MTS assay | Homo sapiens | 5 | ALA4330077 | cell-based format | Scientific Literature | |
| 6. | ALA4331385 | F | Antiproliferative activity against human K562R cells after 72 hrs by MTS assay | Homo sapiens | 5 | ALA4330077 | cell-based format | Scientific Literature | |
| 7. | ALA4331386 | F | Antiproliferative activity against HUVEC after 72 hrs by MTS assay | Homo sapiens | 5 | ALA4330077 | cell-based format | Scientific Literature | |
| 8. | ALA4331387 | F | Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay | Homo sapiens | 5 | ALA4330077 | cell-based format | Scientific Literature | |
| 9. | ALA4331388 | F | Induction of cell cycle arrest in human HCT116 cells assessed as accumulation at G2M phase after 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4330077 | cell-based format | Scientific Literature | |
| 10. | ALA4331389 | F | Induction of cell cycle arrest in human HCT116 cells assessed as accumulation at G2M phase at 10 nM after 24 hrs by propidium iodide staining based flow cytometry relative to control | Homo sapiens | 1 | ALA4330077 | cell-based format | Scientific Literature | |
| 11. | ALA4331390 | F | Antiangiogenic activity in HUVEC assessed as inhibition of tube formation after 2 to 6 hrs by matrigel assay | Homo sapiens | 1 | ALA4330077 | cell-based format | Scientific Literature | |
| 12. | ALA4331391 | F | Antiangiogenic activity in HUVEC assessed as disorganization of the vasculature network at 10 nM after 6 hrs by matrigel assay | Homo sapiens | 1 | ALA4330077 | cell-based format | Scientific Literature | |
| 13. | ALA4331392 | F | Antiangiogenic activity in HUVEC assessed as disorganization of the vasculature network at 50 nM after 2 hrs by matrigel assay | Homo sapiens | 1 | ALA4330077 | cell-based format | Scientific Literature | |
| 14. | ALA4331393 | A | Half life in human liver microsomes at 100 uM in presence of NADPH generating system and glucose-6-phosphate by HPLC-UV-MS analysis | Homo sapiens | 4 | ALA4330077 | microsome format | Scientific Literature | |
| 15. | ALA4331394 | A | Half life in rat liver microsomes at 100 uM in presence of NADPH generating system and glucose-6-phosphate by HPLC-UV-MS analysis | Rattus norvegicus | 4 | ALA4330077 | microsome format | Scientific Literature | |
| 16. | ALA4331395 | P | Lipophilicity, log P of the compound after 24 hrs by HPLC analysis | 4 | ALA4330077 | small-molecule physicochemical format | Scientific Literature | ||
| 17. | ALA4331396 | P | Aqueous solubility of the compound in phosphate buffer at pH 7.4 after 4 hrs by HPLC-UV analysis | 4 | ALA4330077 | small-molecule physicochemical format | Scientific Literature | ||
| 18. | ALA4331397 | A | Drug metabolism in human liver microsomes assessed as cytochrome P450-mediated 3-(1-(2-methylquinolin-4-yl)vinyl)-9H-carbazole metabolite formation at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis | Homo sapiens | 1 | ALA4330077 | microsome format | Scientific Literature | |
| 19. | ALA4331398 | A | Drug metabolism in rat liver microsomes assessed as cytochrome P450-mediated 3-(1-(2-methylquinolin-4-yl)vinyl)-9H-carbazole metabolite formation at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis | Rattus norvegicus | 1 | ALA4330077 | microsome format | Scientific Literature | |
| 20. | ALA4331405 | A | Drug metabolism in human liver microsomes assessed as cytochrome P450-mediated N-demethylated metabolite formation at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis | Homo sapiens | 4 | ALA4330077 | microsome format | Scientific Literature |
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