# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4419373 | Binding | Inhibition of C-terminal 6x-histidine tagged beta-catenin (138 to 686 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 /human BCL9 (350 to 375 residues) protein-protein interactions incubated for 1 hr by Alpha-screen assay | Homo sapiens | 57 | ALA4419168 | assay format | Patent Bioactivity Data | |
2. | ALA4419374 | Binding | Inhibition of C-terminal 6x-histidine tagged beta-catenin (138 to 686 residues) (unknown origin) expressed in Escherichia coli BL21 DE3/N-terminally biotinylated human E-cadherin (824 to 877 residues) protein-protein interactions by Alpha-screen assay | Homo sapiens | 10 | ALA4419168 | assay format | Patent Bioactivity Data | |
3. | ALA4419375 | Binding | Selectivity index, ratio of Ki for inhibition of C-terminal 6x-histidine tagged beta-catenin (138 to 686 residues) (unknown origin) expressed in Escherichia coli BL21 DE3/N-terminally biotinylated human E-cadherin (824 to 877 residues) protein-protein interactions by Alpha-screen assay to Ki for Inhibition of C-terminal 6x-histidine tagged beta-catenin (138 to 686 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 /human BCL9 (350 to 375 residues) protein-protein interactions incubated for 1 hr by Alpha-screen assay | Homo sapiens | 10 | ALA4419168 | assay format | Patent Bioactivity Data | |
4. | ALA4419419 | Functional | Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 47 | ALA4419168 | cell-based format | Patent Bioactivity Data |