# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4399424 | Binding | Inhibition of 20S proteosome beta 1 purified from human HCT116 cells using Z-LLE-AMC as substrate incubated for 30 to 120 mins by fluorimetry | Homo sapiens | 25 | ALA4396921 | assay format | Scientific Literature | |
2. | ALA4399425 | Binding | Inhibition of 20S proteosome beta 2 purified from human HCT116 cells using Boc-LRR-AMC as substrate incubated for 30 to 120 mins by fluorimetry | Homo sapiens | 25 | ALA4396921 | assay format | Scientific Literature | |
3. | ALA4399426 | Binding | Inhibition of 20S proteosome beta 5 purified from human HCT116 cells using Suc-LLVY-AMC as substrate incubated for 30 to 120 mins by fluorimetry | Homo sapiens | 25 | ALA4396921 | assay format | Scientific Literature | |
4. | ALA4399427 | Functional | Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 7 | ALA4396921 | cell-based format | Scientific Literature | |
5. | ALA4399431 | Functional | Induction of apoptosis in human HCT116 cells assessed as viable cells at 1 uM incubated for 48 hrs by annexin-V FITC and propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4396921 | cell-based format | Scientific Literature | |
6. | ALA4399432 | Functional | Induction of apoptosis in human HCT116 cells assessed as early apoptotic cells at 1 uM incubated for 48 hrs by annexin-V FITC and propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4396921 | cell-based format | Scientific Literature | |
7. | ALA4399433 | Functional | Induction of apoptosis in human HCT116 cells assessed as late apoptotic cells at 1 uM incubated for 48 hrs by annexin-V FITC and propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4396921 | cell-based format | Scientific Literature | |
8. | ALA4399434 | Functional | Induction of apoptosis in human HCT116 cells assessed as necrotic cells at 1 uM incubated for 48 hrs by annexin-V FITC and propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4396921 | cell-based format | Scientific Literature | |
9. | ALA4399435 | Functional | Induction of apoptosis in human HCT116 cells assessed as viable cells at 1 uM incubated for 72 hrs by annexin-V FITC and propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4396921 | cell-based format | Scientific Literature | |
10. | ALA4399436 | Functional | Induction of apoptosis in human HCT116 cells assessed as early apoptotic cells at 1 uM incubated for 72 hrs by annexin-V FITC and propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4396921 | cell-based format | Scientific Literature | |
11. | ALA4399437 | Functional | Induction of apoptosis in human HCT116 cells assessed as late apoptotic cells at 1 uM incubated for 72 hrs by annexin-V FITC and propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4396921 | cell-based format | Scientific Literature | |
12. | ALA4399438 | Functional | Induction of apoptosis in human HCT116 cells assessed as necrotic cells at 1 uM incubated for 72 hrs by annexin-V FITC and propidium iodide staining based flow cytometry relative to control | Homo sapiens | 2 | ALA4396921 | cell-based format | Scientific Literature |