# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4418507 | B | Inhibition of recombinant FLAG-tagged EML4-ALK fusion protein (unknown origin) expressed in mouse BA/F3 cells using peptide substrate and ATP incubated for 1 hr by HTRF assay | Homo sapiens | 43 | cell-based format | Patent Bioactivity Data | ||
2. | ALA4418508 | B | Inhibition of recombinant FLAG-tagged EML4-ALK fusion protein (unknown origin) expressed in mouse BA/F3 cells assessed as inhibition of cell growth incubated for 2 days by alamar blue dye based assay | Homo sapiens | 43 | cell-based format | Patent Bioactivity Data | ||
3. | ALA4418511 | F | Antitumor activity against EML4-ALK fusion protein harboring human NCI-H2228 cells xenografted in NOD/SCID mouse assessed as inhibition of tumor growth at 1 mg/kg, po dosed once daily for 14 days starting 3 weeks of tumor cell inoculation and measured every other day relative to untreated control | Homo sapiens | 3 | organism-based format | Patent Bioactivity Data |