| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4361953 | Binding | Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysis | Homo sapiens | 23 | ALA4359859 | subcellular format | Scientific Literature | |
| 2. | ALA4361954 | Binding | Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysis | Homo sapiens | 22 | ALA4359859 | assay format | Scientific Literature | |
| 3. | ALA4361955 | Binding | Selectivity ratio of IC50 for human placental cytosolic fraction 17beta-HSD1 to IC50 for human placental microsomal fraction 17beta-HSD2 | Homo sapiens | 23 | ALA4359859 | assay format | Scientific Literature | |
| 4. | ALA4361957 | Binding | Inhibition of mouse liver homogenate 17beta-HSD2 at 50 nM using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysis relative to control | Mus musculus | 8 | ALA4359859 | tissue-based format | Scientific Literature | |
| 5. | ALA4361958 | Binding | Inhibition of recombinant mouse 17beta-HSD1 expressed in HEK293 cells at 1 uM using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysis relative to control | Mus musculus | 22 | ALA4359859 | cell-based format | Scientific Literature | |
| 6. | ALA4361959 | ADME | Half life in human liver S9 fraction at 1 uM measured in presence of NADPH generating system | Homo sapiens | 23 | ALA4359859 | subcellular format | Scientific Literature | |
| 7. | ALA4361961 | Physicochemical | Aqueous solubility of the compound in pH 7.2 phosphate buffered saline/DMSO | 23 | ALA4359859 | small-molecule physicochemical format | Scientific Literature |
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