| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4330038 | B | Inhibition of human ABHD16A expressed in HEK293 cells assessed as residual activity at 10 uM preincubated for 30 mins followed by 1-LG substrate addition and measured after 90 to 120 mins by fluorometric assay relative to control | Homo sapiens | 20 | ALA4325934 | cell-based format | Scientific Literature | |
| 2. | ALA4330039 | A | Inhibition of human ABHD12 expressed in HEK293 cells assessed as residual activity at 10 uM preincubated for 30 mins followed by 1-AG substrate addition and measured after 90 to 120 mins by fluorometric assay relative to control | Homo sapiens | 20 | ALA4325934 | cell-based format | Scientific Literature | |
| 3. | ALA4330040 | B | Inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 1-LG substrate addition and measured after 90 to 120 mins by fluorometric assay | Homo sapiens | 3 | ALA4325934 | cell-based format | Scientific Literature | |
| 4. | ALA4330041 | B | Reversible inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 40 fold compound dilution and subsequent 1-LG substrate addition and measured at 30 mins time interval for 120 mins by fluorometric assay | Homo sapiens | 3 | ALA4325934 | cell-based format | Scientific Literature | |
| 5. | ALA4330042 | B | Inhibition of human ABHD16A expressed in HEK293 cells assessed as residual activity at 100 uM preincubated for 30 mins followed by 1-LG substrate addition and measured after 90 to 120 mins by fluorometric assay relative to control | Homo sapiens | 2 | ALA4325934 | cell-based format | Scientific Literature | |
| 6. | ALA4330043 | B | Ratio of IC50 for reversible inhibition of human ABHD16A expressed in HEK293 cells to IC50 for inhibition of human ABHD16A expressed in HEK293 cells | Homo sapiens | 3 | ALA4325934 | cell-based format | Scientific Literature | |
| 7. | ALA4330044 | B | Inhibition of TAMRA-FP binding to ABHD16A in rat cerebellar membranes preincubated for 1 hr followed by TAMRA-FP addition measured after 1 hr by fluorescence based ABPP analysis | Rattus norvegicus | 1 | ALA4325934 | cell membrane format | Scientific Literature |
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