#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4353688	Binding	Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as substrate and 2OG as cosubstrate pre-incubated for 10 mins before substrate addition followed by centrifugation for 1 min and measured after 20 mins by AlphaScreen assay	Homo sapiens	33	ALA4350996	assay format	Scientific Literature
2.	ALA4353689	Binding	Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as substrate and 2OG as cosubstrate pre-incubated for 10 mins before substrate addition followed by centrifugation for 1 min and measured after 20 mins by AlphaScreen assay	Homo sapiens	33	ALA4350996	cell-based format	Scientific Literature
3.	ALA4353690	Binding	Inhibition of KDM5B (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG as cosubstrate pre-incubated for 15 mins before substrate addition followed by centrifugation for 15 secs and measured after 20 mins by Alphascreen assay	Homo sapiens	33	ALA4350996	single protein format	Scientific Literature
4.	ALA4353691	Binding	Inhibition of KDM5C (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG as cosubstrate pre-incubated for 15 mins before substrate addition followed by centrifugation for 15 secs and measured after 20 mins by Alphascreen assay	Homo sapiens	33	ALA4350996	single protein format	Scientific Literature
5.	ALA4353692	Binding	Inhibition of KDM2A (unknown origin) by Alphascreen assay	Homo sapiens	6	ALA4350996	single protein format	Scientific Literature
6.	ALA4353693	Binding	Inhibition of KDM3A (unknown origin) by Alphascreen assay	Homo sapiens	6	ALA4350996	single protein format	Scientific Literature
7.	ALA4353694	Binding	Inhibition of KDM6B (unknown origin) by Alphascreen assay	Homo sapiens	5	ALA4350996	single protein format	Scientific Literature
8.	ALA4353730	Binding	Binding affinity to KDM4A (unknown origin)	Homo sapiens	8	ALA4350996	single protein format	Scientific Literature
9.	ALA4353731	Binding	Binding affinity to KDM5B (unknown origin)	Homo sapiens	8	ALA4350996	single protein format	Scientific Literature
10.	ALA4353732	ADME	Apparent permeability of the compound in human Caco2 cells from apical to basolateral side at 10 uM after 2 hr by LC/MS/MS analysis	Homo sapiens	33	ALA4350996	cell-based format	Scientific Literature
11.	ALA4353733	Binding	Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in HEK293T cells measured after 30 mins by chemiluminescence based cellular target engagement assay	Homo sapiens	8	ALA4350996	cell-based format	Scientific Literature
12.	ALA4353734	Binding	Binding affinity to recombinant human N-terminal KDM5B (26 to 772 residues) fused with ePL-tagged C-terminal transfected in HEK293T cells measured after 30 mins by chemiluminescence based cellular target engagement assay	Homo sapiens	8	ALA4350996	cell-based format	Scientific Literature
13.	ALA4353735	Binding	Inhibition of FLAG tagged full length wild type human KDM4A transfected in HeLa cells assessed as decrease in demethylation of H3K9Me3 measured after 24 hrs by cell analyser based immunofluorescence assay	Homo sapiens	7	ALA4350996	cell-based format	Scientific Literature
14.	ALA4353737	Binding	Inhibition of full length human wild type KDM5B transfected in HeLa cells assessed as decrease in demethylation of H3K4Me3 measured after 24 hrs by cell analyser based immunofluorescence assay	Homo sapiens	8	ALA4350996	cell-based format	Scientific Literature