#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4424848	B	Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins followed by substrate addition and measured after 10 mins by HTRF assay	Homo sapiens	21	ALA4422686	single protein format	Scientific Literature
2.	ALA4424849	B	Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-stimulation and measured after 6 hrs by ELISA	Mus musculus	21	ALA4422686	single protein format	Scientific Literature
3.	ALA4424850	P	Aqueous solubility of the compound in pH 7.2 phosphate buffered saline		21	ALA4422686	small-molecule physicochemical format	Scientific Literature
4.	ALA4424851	A	Stability in human liver S9 fraction assessed as parent compound remaining at 5 uM preincubated for 5 mins followed by NADPH addition and measured after 60 mins by LC-MS/MS analysis	Homo sapiens	21	ALA4422686	subcellular format	Scientific Literature
5.	ALA4424852	A	Stability in Sprague-Dawley rat liver S9 fraction assessed as parent compound remaining at 5 uM preincubated for 5 mins followed by NADPH addition and measured after 60 mins by LC-MS/MS analysis	Rattus norvegicus	21	ALA4422686	subcellular format	Scientific Literature
6.	ALA4424853	A	Stability in CD-1 mouse liver S9 fraction assessed as parent compound remaining at 5 uM preincubated for 5 mins followed by NADPH addition and measured after 60 mins by LC-MS/MS analysis	Mus musculus	21	ALA4422686	subcellular format	Scientific Literature
7.	ALA4424854	F	Invivo inhibition of CSF1R in CSF1-induced DBA/1J mouse assessed as reduction in LPS-induced IL6 production at 10 mg/kg, po treated for 1 hr prior to CSF1-stimulation followed by LPS-addition and measured after 2 hrs by ELISA relative to control	Mus musculus	21	ALA4422686	organism-based format	Scientific Literature
8.	ALA4424855	F	Invivo inhibition of CSF1R in CSF1-induced DBA/1J mouse assessed as reduction in LPS-induced IL6 production at 10 mg/kg, po treated for 6 hrs prior to CSF1-stimulation followed by LPS-addition and measured after 2 hrs by ELISA relative to control	Mus musculus	21	ALA4422686	organism-based format	Scientific Literature