| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4313193 | B | Inhibition of HIV1 NL4-3 protease I84V mutant expressed in Escherichia coli TAP-106 cells using EDANS/DABCYL-labelled 10-amino acid containing natural MA/CA cleavage site as substrate preincubated for 1 hr followed by substrate addition and measured for 60 mins by FRET assay | Human immunodeficiency virus 1 | 15 | cell-based format | Scientific Literature | ||
| 2. | ALA4313194 | B | Inhibition of HIV1 NL4-3 protease I50V/A71V mutant expressed in Escherichia coli TAP-106 cells using EDANS/DABCYL-labelled 10-amino acid containing natural MA/CA cleavage site as substrate preincubated for 1 hr followed by substrate addition and measured for 60 mins by FRET assay | Human immunodeficiency virus 1 | 15 | cell-based format | Scientific Literature | ||
| 3. | ALA4313195 | F | Antiviral activity against wild-type HIV1 NL4-3 infected in human TZM-bl cells preincubated for 18 hrs followed by viral infection and measured after 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 15 | organism-based format | Scientific Literature | ||
| 4. | ALA4313196 | F | Antiviral activity against multidrug-resistant HIV1 NL4-3 SLK19 infected in human TZM-bl cells preincubated for 18 hrs followed by viral infection and measured after 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 15 | organism-based format | Scientific Literature | ||
| 5. | ALA4313197 | F | Antiviral activity against multidrug-resistant HIV1 NL4-3 VSL20 infected in human TZM-bl cells preincubated for 18 hrs followed by viral infection and measured after 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 15 | organism-based format | Scientific Literature | ||
| 6. | ALA4313198 | F | Antiviral activity against multidrug-resistant HIV1 NL4-3 KY24 infected in human TZM-bl cells preincubated for 18 hrs followed by viral infection and measured after 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 15 | organism-based format | Scientific Literature | ||
| 7. | ALA4313199 | F | Selectivity ratio of EC50 for antiviral activity against multidrug-resistant HIV1 NL4-3 SLK19 infected in human TZM-bl cells to EC50 for antiviral activity against wild-type HIV1 NL4-3 infected in human TZM-bl cells | 15 | cell-based format | Scientific Literature | |||
| 8. | ALA4313200 | F | Selectivity ratio of EC50 for antiviral activity against multidrug-resistant HIV1 NL4-3 VSL20 infected in human TZM-bl cells to EC50 for antiviral activity against wild-type HIV1 NL4-3 infected in human TZM-bl cells | 15 | cell-based format | Scientific Literature | |||
| 9. | ALA4313201 | F | Selectivity ratio of EC50 for antiviral activity against multidrug-resistant HIV1 NL4-3 KY24 infected in human TZM-bl cells to EC50 for antiviral activity against wild-type HIV1 NL4-3 infected in human TZM-bl cells | 15 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!