# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4323269 | B | Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Homo sapiens | 32 | ALA4321820 | cell-based format | Scientific Literature | |
2. | ALA4323270 | B | Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured every 2.5 mins for 30 mins by Amplex-Red oxidation assay | Bos taurus | 32 | ALA4321820 | tissue-based format | Scientific Literature | |
3. | ALA4323271 | A | Substrate activity at recombinant human SSAO assessed as compound oxidation by measuring oxidative turnover at 30 uM measured for 40 mins by horseradish peroxidase-coupled amplex red reagent-based fluorometric assay relative to DMSO | Homo sapiens | 22 | ALA4321820 | single protein format | Scientific Literature | |
4. | ALA4323272 | A | Substrate activity at AOC4 in dog serum assessed as compound oxidation by measuring oxidative turnover at 30 uM measured for 40 mins by horseradish peroxidase-coupled amplex red reagent-based fluorometric assay relative to DMSO | Canis lupus familiaris | 15 | ALA4321820 | cell-free format | Scientific Literature | |
5. | ALA4323304 | B | Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells assessed as recovery of enzyme activity at 10XIC50 preincubated with bound enzyme for 30 mins followed by drug wash-out and later incubated with putrescine substrate and measured after 30 mins by Amplex-Red oxidation assay | Homo sapiens | 1 | ALA4321820 | cell-based format | Scientific Literature | |
6. | ALA4323305 | A | Substrate activity at recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells assessed as oxidative turnover at 30 uM measured after 30 mins by horseradish peroxidase-coupled amplex red reagent-based fluorescence assay relative to DMSO | Homo sapiens | 2 | ALA4321820 | cell-based format | Scientific Literature |