# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4402085 | Functional | Agonist activity at human RXFP3 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated for 30 mins followed by forskolin-stimulation and measured after 30 mins by HTRF assay | Homo sapiens | 4 | ALA4400563 | cell-based format | Scientific Literature | |
2. | ALA4402086 | Functional | Agonist activity at human RXFP3 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated for 30 mins followed by forskolin-stimulation and measured after 30 mins by HTRF assay relative to relaxin-3 | Homo sapiens | 4 | ALA4400563 | cell-based format | Scientific Literature | |
3. | ALA4402087 | Binding | Displacement of [125I]-R3/I5 from human RXFP3 expressed in CHOK1 cell membranes by radioligand binding assay | Homo sapiens | 1 | ALA4400563 | cell-based format | Scientific Literature | |
4. | ALA4402088 | Functional | Agonist activity at human RXFP4 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated for 30 mins followed by forskolin-stimulation and measured after 30 mins by HTRF assay | Homo sapiens | 4 | ALA4400563 | cell-based format | Scientific Literature | |
5. | ALA4402089 | Functional | Agonist activity at human RXFP4 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated for 30 mins followed by forskolin-stimulation and measured after 30 mins by HTRF assay relative to relaxin-3 | Homo sapiens | 4 | ALA4400563 | cell-based format | Scientific Literature | |
6. | ALA5033950 | Functional | Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs by TR-FRET assay | Homo sapiens | 56 | ALA5032539 | cell-based format | Scientific Literature | |
7. | ALA5033951 | Functional | Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as maximal inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs by TR-FRET assay relative to relaxin 3 | Homo sapiens | 56 | ALA5032539 | cell-based format | Scientific Literature | |
8. | ALA5033952 | Functional | Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as beta arrestin-2 recruitment measured after 4 hrs by beta-galactosidase based beta arrestin2 recruitment assay | Homo sapiens | 4 | ALA5032539 | cell-based format | Scientific Literature | |
9. | ALA5033954 | Binding | Displacement of [125I]R3/I5 from human RXFP3 expressed in human CHO-K1 cells incubated for 1 hr by microplate scintillation counting analysis | Homo sapiens | 4 | ALA5032539 | cell-based format | Scientific Literature |