| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4401751 | T | Mitochondrial toxicity in human HepG2 cells assessed as reduction in cell viability after 24 hrs in presence of galactose by CellTiter-Glo assay | Homo sapiens | 4 | ALA4400546 | cell-based format | Scientific Literature | |
| 2. | ALA4401753 | T | Mitochondrial toxicity in human HepG2 cells assessed as reduction in cell viability after 24 hrs in presence of glucose by CellTiter-Glo assay | Homo sapiens | 4 | ALA4400546 | cell-based format | Scientific Literature | |
| 3. | ALA4401754 | F | Potentiation of rifampicin-induced antibacterial activity against Streptococcus pneumoniae D39 at 2 times MIC after 20 hrs by checkerboard assay | Streptococcus pneumoniae | 1 | ALA4400546 | organism-based format | Scientific Literature | |
| 4. | ALA4401755 | F | Potentiation of penicillin-induced antibacterial activity against Streptococcus pneumoniae D39 at 2 times MIC after 20 hrs by checkerboard assay | Streptococcus pneumoniae | 1 | ALA4400546 | organism-based format | Scientific Literature | |
| 5. | ALA4401756 | F | Potentiation of levofloxacin-induced antibacterial activity against Streptococcus pneumoniae D39 at 2 times MIC after 20 hrs by checkerboard assay | Streptococcus pneumoniae | 1 | ALA4400546 | organism-based format | Scientific Literature | |
| 6. | ALA4401757 | F | Antibacterial activity against Streptococcus pneumoniae D39 after 20 hrs by CLSI-based microdilution method | Streptococcus pneumoniae | 51 | ALA4400546 | organism-based format | Scientific Literature | |
| 7. | ALA4401758 | A | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue assay | Homo sapiens | 51 | ALA4400546 | cell-based format | Scientific Literature | |
| 8. | ALA4401759 | F | Bactericidal activity against Streptococcus pneumoniae D39 after 24 hrs | Streptococcus pneumoniae | 3 | ALA4400546 | organism-based format | Scientific Literature | |
| 9. | ALA4401760 | F | Bacteriostatic activity against Streptococcus pneumoniae D39 at 1 to 5 times MIC after 18 hrs by time-kill assay | Streptococcus pneumoniae | 1 | ALA4400546 | organism-based format | Scientific Literature | |
| 10. | ALA4401762 | F | Bacteriostatic activity against Streptococcus pneumoniae D39 up 100 times MIC after 18 hrs by time-kill assay | Streptococcus pneumoniae | 1 | ALA4400546 | organism-based format | Scientific Literature | |
| 11. | ALA4401763 | F | Antibacterial activity against Streptococcus pneumoniae R6 after 20 hrs by CLSI-based microdilution method | Streptococcus pneumoniae | 3 | ALA4400546 | organism-based format | Scientific Literature | |
| 12. | ALA4401764 | F | Bacteriostatic activity against Streptococcus pneumoniae D39 assessed as resistant frequency at 4 to 16 times MIC after 24 hrs by time-kill assay | Streptococcus pneumoniae | 1 | ALA4400546 | organism-based format | Scientific Literature | |
| 13. | ALA4401765 | F | Antibacterial activity against amoxicillin/penicillin/cefotaxime/erythromycin/tetracycline-resistant Streptococcus pneumoniae TH2784 (19F) after 20 hrs by CLSI-based microdilution method | Streptococcus pneumoniae | 3 | ALA4400546 | organism-based format | Scientific Literature | |
| 14. | ALA4401766 | F | Antibacterial activity against amoxicillin/penicillin/chloramphenicol/erythromycin/meropenem/cefotaxime-resistant Streptococcus pneumoniae TH2582 (19A) after 20 hrs by CLSI-based microdilution method | Streptococcus pneumoniae | 3 | ALA4400546 | organism-based format | Scientific Literature | |
| 15. | ALA4401767 | F | Antibacterial activity against amoxicillin/penicillin/erythromycin/ertapenem/moxifloxacin/cefotaxime-resistant Streptococcus pneumoniae TH2889 (6B) after 20 hrs by CLSI-based microdilution method | Streptococcus pneumoniae | 3 | ALA4400546 | organism-based format | Scientific Literature | |
| 16. | ALA4401768 | F | Antibacterial activity against penicillin/erythromycin/meropenem/tetracycline-resistant Streptococcus pneumoniae TH2863 (19F) after 20 hrs by CLSI-based microdilution method | Streptococcus pneumoniae | 3 | ALA4400546 | organism-based format | Scientific Literature | |
| 17. | ALA4401769 | F | Antibacterial activity against optochin-resistant Streptococcus pneumoniae R6 expressing atpE G142C mutant after 20 hrs by CLSI-based microdilution method | Streptococcus pneumoniae | 3 | ALA4400546 | organism-based format | Scientific Literature | |
| 18. | ALA4401770 | F | Antibacterial activity against optochin-resistant Streptococcus pneumoniae R6 expressing atpE G145A mutant after 20 hrs by CLSI-based microdilution method | Streptococcus pneumoniae | 3 | ALA4400546 | organism-based format | Scientific Literature | |
| 19. | ALA4401771 | B | Inhibition of wild-type Streptococcus pneumoniae D39 ATP synthase atpE assessed as reduction in intracellular pH measured at 5 mins intervals by pH-sensitive GFP-based fluorescence assay | Streptococcus pneumoniae D39 | 1 | ALA4400546 | cell-based format | Scientific Literature | |
| 20. | ALA4401772 | B | Inhibition of wild-type Streptococcus pneumoniae D39 ATP synthase atpE assessed as intracellular pH at 0.0625 ug/ml measured at 5 mins by pH-sensitive GFP-based fluorescence assay (Rvb = 7.34 +/- 0.04 No_unit) | Streptococcus pneumoniae D39 | 1 | ALA4400546 | cell-based format | Scientific Literature |
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