| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4481216 | A | Drug degradation in rat liver microsomes at 1 uM measured over 60 mins by LC-MS/MS analysis | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
| 2. | ALA4481217 | A | Drug degradation in human liver microsomes at 1 uM measured over 60 mins by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 3. | ALA4481218 | A | Degradation half life in rat liver microsomes at 1 uM by LC-MS/MS analysis | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
| 4. | ALA4481219 | A | Degradation half life in human liver microsomes at 1 uM by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 5. | ALA4481220 | A | Drug degradation in rat plasma at 1000 ng/ml measured over 240 mins by LC-MS/MS analysis | Rattus norvegicus | 3 | cell-free format | Scientific Literature | ||
| 6. | ALA4481221 | A | Degradation half life in rat plasma at 1000 ng/ml by LC-MS/MS analysis | Rattus norvegicus | 3 | cell-free format | Scientific Literature | ||
| 7. | ALA4481222 | A | Drug degradation in human plasma at 1000 ng/ml measured over 240 mins by LC-MS/MS analysis | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
| 8. | ALA4481223 | A | Degradation half life in human plasma at 1000 ng/ml by LC-MS/MS analysis | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
| 9. | ALA4481225 | B | Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current at 30 nM by two-electrode voltage clamp electrophysiology | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4481226 | B | Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current at 10 nM by two-electrode voltage clamp electrophysiology | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4481227 | B | Inhibition of recombinant human GlyT2a expressed in expressed in Xenopus laevis oocytes assessed as reduction in [3H]glycine uptake at 0.1 to 1 uM pretreated for 2 mins followed by [3H]glycine addition and measured after 30 mins by scintillation counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4481228 | B | Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in [3H]glycine uptake at 0.1 to 1 uM pretreated for 2 mins followed by [3H]glycine addition and measured after 30 mins by scintillation counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4481229 | B | Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp electrophysiology | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
| 14. | ALA4481230 | B | Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp electrophysiology | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
| 15. | ALA4481231 | B | Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp electrophysiology relative to control | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
| 16. | ALA4481261 | B | Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current at 1 uM by two-electrode voltage clamp electrophysiology | Homo sapiens | 1 | cell-based format | Scientific Literature |
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