# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4345696 | B | Inhibition of recombinant His-tagged human BCL6 expressed in Escherichia coli BL21 AI cell incubated for 2 hrs by TR-FRET assay | Homo sapiens | 44 | ALA4342505 | assay format | Scientific Literature | |
2. | ALA4345697 | P | Kinetic solubility in HEPES buffer containing 5% DMSO at pH 8 incubated for 20 hrs by NMR analysis | 48 | ALA4342505 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4345700 | B | Induction of BCL6 degradation in human SUDHL-4 cells incubated for 2 hrs by immunofluorescence analysis | Homo sapiens | 28 | ALA4342505 | cell-based format | Scientific Literature | |
4. | ALA4345701 | B | Induction of BCL6 degradation in human SUDHL-4 cells at 10 uM incubated for 2 hrs by immunofluorescence analysis relative to control | Homo sapiens | 24 | ALA4342505 | cell-based format | Scientific Literature | |
5. | ALA4345705 | A | Metabolic stability in CD-1 mouse liver microsomes assessed as intrinsic clearance at 1 uM measured upt0 30 mins by LC-MS/MS analysis | Mus musculus | 14 | ALA4342505 | microsome format | Scientific Literature | |
6. | ALA4345706 | B | Induction of BCL6 degradation in human OCI-LY1 cells incubated for 2 hrs by MSD electrochemiluminescent immunoassay | Homo sapiens | 5 | ALA4342505 | cell-based format | Scientific Literature | |
7. | ALA4345707 | B | Induction of BCL6 degradation in human KARPAS422 cells incubated for 2 hrs by MSD electrochemiluminescent immunoassay | Homo sapiens | 5 | ALA4342505 | cell-based format | Scientific Literature | |
8. | ALA4345708 | F | Antiproliferative activity agianst human SUDHL4 cells assessed as growth inhibition incubated for 14 days by CellTiter Glo reagent based assay | Homo sapiens | 5 | ALA4342505 | cell-based format | Scientific Literature | |
9. | ALA4345709 | F | Antiproliferative activity agianst human OCI-LY1 cells assessed as growth inhibition incubated for 14 days by CellTiter Glo reagent based assay | Homo sapiens | 5 | ALA4342505 | cell-based format | Scientific Literature | |
10. | ALA4345710 | F | Antiproliferative activity agianst human OCI-LY3 cells assessed as growth inhibition incubated for 14 days by CellTiter Glo reagent based assay | Homo sapiens | 5 | ALA4342505 | assay format | Scientific Literature | |
11. | ALA4345731 | P | Lipophilicity, log D of compound at pH 7.4 | 14 | ALA4342505 | small-molecule physicochemical format | Scientific Literature |